Bacterial proton motive force as an unprecedented target to control antimicrobial resistance

B Yang, Z Tong, J Shi, Z Wang… - Medicinal Research …, 2023 - Wiley Online Library
Novel antibacterial therapies are urgently required to tackle the increasing number of
multidrug‐resistant pathogens. Identification of new antimicrobial targets is critical to avoid …

Phage Paride can kill dormant, antibiotic-tolerant cells of Pseudomonas aeruginosa by direct lytic replication

E Maffei, AK Woischnig, MR Burkolter, Y Heyer… - Nature …, 2024 - nature.com
Bacteriophages are ubiquitous viral predators that have primarily been studied using fast-
growing laboratory cultures of their bacterial hosts. However, microbial life in nature is …

[HTML][HTML] Antibiotic tolerance: targeting bacterial survival

L Boeck - Current Opinion in Microbiology, 2023 - Elsevier
Antimicrobial susceptibility testing is the cornerstone of antibiotic treatments. Yet, active
drugs are frequently unsuccessful in vivo and most clinical trials investigating antibiotics fail …

Phage Paride hijacks bacterial stress responses to kill dormant, antibiotic-tolerant cells

E Maffei, M Burkolter, Y Heyer, A Egli, U Jenal… - BioRxiv, 2022 - biorxiv.org
Bacteriophages are fierce viral predators with no regard for pathogenicity or antibiotic
resistance of their bacterial hosts,. Despite early recognition of their therapeutic potential …

Relative fitness of wild-type and phage-resistant pyomelanogenic P. aeruginosa and effects of combinatorial therapy on resistant formation

AS Mary, N Kalangadan, J Prakash, S Sundaresan… - Heliyon, 2024 - cell.com
Bacteriophages, the natural predators of bacteria, are incredibly potent candidates to
counteract antimicrobial resistance (AMR). However, the rapid development of phage …

Elucidation of the clinical relevance and potential mechanisms of persistence in Streptococcus pneumoniae

N Geerts - 2024 - repository.uantwerpen.be
Infectious diseases exist already for millennia and so does antimicrobial therapy. The past
100 years, major advances were accomplished into the fight against infectious diseases …

[PDF][PDF] Nele GEERTS

P Cos - 2024 - repository.uantwerpen.be
PREFACE iv over het werk, maar ook over vanalle andere dingen! Ik heb er ook heel erg
van genoten om samen te sporten voor of na het werk☺. Ons avontuur op de Brusselse ring …

[PDF][PDF] Andrew David Campey

IM Of - 2024 - ore.exeter.ac.uk
Antibiotic resistance represents one of the most pressing challenges in global health,
threatening to render many of our most potent antimicrobial agents ineffective and lead to a …