Wnt/β-catenin signaling has been broadly implicated in human cancers and experimental
cancer models of animals. Aberrant activation of Wnt/β-catenin signaling is tightly linked with …

Proliferation is an important part of cancer development and progression. This is manifest by
altered expression and/or activity of cell cycle related proteins. Constitutive activation of …

This review addresses the oncopharmacological properties of curcumin at the molecular
level. First, the interactions between curcumin and its molecular targets are addressed on …

Cystathionine-β-synthase (CBS), the first (and rate-limiting) enzyme in the transsulfuration
pathway, is an important mammalian enzyme in health and disease. Its biochemical …

Despite significant advances in treatment modalities over the last decade, neither the
incidence of the disease nor the mortality due to cancer has altered in the last thirty years …

Simple Summary Osteosarcoma (OS), the most common primary bone tumor, mainly affects
children and adolescents. Unfortunately, in some cases, the absence of response to …

Cancer metastasis is the major cause of cancer-related death, and chemoprevention is
defined as the use of natural or synthetic substances to prevent cancer formation or cancer …

The association between chronic inflammation and cancer development has been well
documented. One of the major obstacles in cancer treatment is the persistent autocrine and …

Curcumin derived from the tropical plant Curcuma longa has a long history of use as a
dietary agent, food preservative, and in traditional Asian medicine. It has been used for …

Curcumin is a natural polyphenol phytochemical derived from turmeric with antioxidant, anti-
inflammatory, and anticancer properties but is concerned about poor solubility in water …