[PDF][PDF] Solid dispersion as a technical solution to boost the dissolution rate and bioavailability of poorly water-soluble drugs

MS Attia, AA Hasan, FES Ghazy, E Gomaa… - Indian Journal of …, 2021 - ijper.org
Solid dispersion (SD) is one of the oldest and widely utilized techniques to improve the
solubility of slowly dissolving drugs. A variety of pharmaceutically compatible additives using …

Modification of the Physicochemical Properties of Active Pharmaceutical Ingredients via Lyophilization

A Taldaev, DI Pankov, RP Terekhov, AK Zhevlakova… - Pharmaceutics, 2023 - mdpi.com
Bioavailability is an important biopharmaceutical characteristic of active pharmaceutical
ingredients (APIs) that is often correlated with their solubility in water. One of the methods of …

Optimization of injectable PLGA in-situ forming implants of anti-psychotic risperidone via Box-Behnken Design

TM Ibrahim, NA El-Megrab, HM El-Nahas - Journal of Drug Delivery …, 2020 - Elsevier
The current study aims to develop in-situ forming implants (ISFI) of anti-psychotic risperidone
to customize schizophrenia therapy. Non-adherence to treatment is the most prevalent …

Bactericidal activity of usnic acid-chitosan nanoparticles against persister cells of biofilm-forming pathogenic bacteria

F Khan, H Yu, YM Kim - Marine Drugs, 2020 - mdpi.com
The present study aimed to prepare usnic acid (UA)-loaded chitosan (CS) nanoparticles (UA-
CS NPs) and evaluate its antibacterial activity against biofilm-forming pathogenic bacteria …

[PDF][PDF] Recent strategies for improving solubility and oral bioavailability of piperine

H Salsabila, L Fitriani, E Zaini - Int. J. Appl. Pharm, 2021 - researchgate.net
L.), has long been used in Ayurveda and traditional Chinese medicine (TCM). This
compound has remarkable potential pharmacological properties, including being anti …

[PDF][PDF] Enhancing the solubility and dissolution rate of piperine via preparation of piperine–hydroxypropyl methylcellulose 2910 solid dispersion system using freeze …

L Fitriani, S Tirtania, S Umar… - Journal of Pharmacy & …, 2024 - pharmaexcipients.com
Context: Piperine is the main secondary metabolite isolated from the family Piperaceae. This
biologically active ingredient has many pharmacological effects, though its low water …

Hydrogel Formulation of Usnic Acid and Antibacterial Activity Test Against Propionibacterium acne

L Fitriani, Afifah, F Ismed, A Bakhtiar - Scientia Pharmaceutica, 2019 - mdpi.com
Usnic acid is known for its remarkable antimicrobial activity. The aim of this research was to
formulate hydrogel of usnic acid and evaluate the antibacterial activity against …

[PDF][PDF] Solid dispersion of usnic acid-PVP K30 and evaluation of antioxidant activity

L Fitriani, E Rismawati, S Umar, E Zaini - Rasayan J. Chem, 2018 - rasayanjournal.co.in
Usnic acid, a compound produced by Usnea sp, has been reported for anti-oxidant activity.
However, the use of usnic acid is still finite due to poor solubility in water. One of the …

Solid Dispersion of Tenoxicam–HPMC by Freeze-Drying: Solid State Properties, Dissolution Study, and Analgesic Activity in Mice

S Umar, H Usman, H Salsabila, E Zaini - Open Access Macedonian …, 2022 - oamjms.eu
AIM: The aim of this study was to prepare solid dispersion of tenoxicam with hydroxypropyl
methylcellulose (HPMC) to improve solubility, dissolution rate, and in vivo analgesic activity …

Preparation and Characterization of Usnic Acid Nanocrystals with the Wet Grinding Method Using a Planetary Ball Mill.

R Wahyuni, H Lucida, G Revilla… - Tropical Journal of …, 2024 - search.ebscohost.com
Usnic acid is a potential active pharmaceutical ingredient derived from Usnea sp. It has a
low bioavailability because of poor aqueous solubility. Particle size reduction by nanosizing …