Methicillin-resistant Staphylococcus aureus (MRSA): antibiotic-resistance and the biofilm phenotype

KM Craft, JM Nguyen, LJ Berg, SD Townsend - MedChemComm, 2019 - pubs.rsc.org
Staphylococcus aureus (S. aureus) is an asymptomatic colonizer of 30% of all human
beings. While generally benign, antibiotic resistance contributes to the success of S. aureus …

[HTML][HTML] Therapeutic strategies against bacterial biofilms

Y Bi, G Xia, C Shi, J Wan, L Liu, Y Chen, Y Wu… - Fundamental …, 2021 - Elsevier
The emergence of multi-drug resistance makes bacterial infection a major threat to public
health and economy. The formation of bacterial biofilms is one of the main reasons of …

Stimuli-responsive therapeutic systems for the treatment of diabetic infected wounds

Y Hu, H Li, X Lv, Y Xu, Y Xie, L Yuwen, Y Song, S Li… - Nanoscale, 2022 - pubs.rsc.org
Diabetic wound infection is a common disease that has significantly reduced people's
quality of life. Although tremendous achievements have been made in clinical treatment, the …

[HTML][HTML] Recent advances in nanomaterial-based wound-healing therapeutics

A Naskar, K Kim - Pharmaceutics, 2020 - mdpi.com
Nanomaterial-based wound healing has tremendous potential for treating and preventing
wound infections with its multiple benefits compared with traditional treatment approaches …

Preparation, properties and drug controlled release of chitin-based hydrogels: An updated review

J Liao, B Hou, H Huang - Carbohydrate Polymers, 2022 - Elsevier
Chitin, as the second abundant biopolymers on earth after cellulose, has been used for
synthesis of hydrogels in a wide range of applications due to its biocompatibility …

Development of antibiofilm therapeutics strategies to overcome antimicrobial drug resistance

S Nadar, T Khan, SG Patching, A Omri - Microorganisms, 2022 - mdpi.com
A biofilm is a community of stable microorganisms encapsulated in an extracellular matrix
produced by themselves. Many types of microorganisms that are found on living hosts or in …

Functional hydrogels for diabetic wound management

D Gao, Y Zhang, DT Bowers, W Liu, M Ma - APL bioengineering, 2021 - pubs.aip.org
Diabetic wounds often have a slow healing process and become easily infected owing to
hyperglycemia in wound beds. Once planktonic bacterial cells develop into biofilms, the …

Rational design of smart hydrogels for biomedical applications

Y Zhang, Y Huang - Frontiers in Chemistry, 2021 - frontiersin.org
Hydrogels are polymeric three-dimensional network structures with high water content. Due
to their superior biocompatibility and low toxicity, hydrogels play a significant role in the …

Thermoresponsive polymers with LCST transition: synthesis, characterization, and their impact on biomedical frontiers

Y Yuan, K Raheja, NB Milbrandt, S Beilharz… - RSC Applied …, 2023 - pubs.rsc.org
Advances in thermoresponsive materials have significantly impacted many biomedical
fields. The unique behavior of reversible phase transition close to the physiological …

Inhibition and eradication of bacterial biofilm using polymeric materials

A Banerjee, P Chowdhury, K Bauri, B Saha… - Biomaterials Science, 2023 - pubs.rsc.org
Biofilms, ubiquitous in nature, are three-dimensional complex microbial communities
sheathed in a self-secreted extracellular polymeric matrix. Infections caused by these …