Countless times each day, the acute inflammatory response protects us from invading
microbes, injuries, and insults from within, as in surgery-induced tissue injury. These …

Polyunsaturated fatty acids (PUFAs) are important components of the diet of mammals. Their
role was first established when the essential fatty acids (EFAs) linoleic acid and α-linolenic …

Neutrophils are the primary cell type involved in lung ischemia-reperfusion injury (IRI), which
remains a frequent and morbid complication after organ transplantation. Endogenous lipid …

Docosahexaenoic acid (C22: 6 n-3, DHA) is the precursor of specialized pro-resolving lipid
mediators (SPMs), such as resolvin, protectin, and maresin families which have been …

Pneumonia is inflammation in the lungs, which is usually caused by an infection. The
symptoms of pneumonia can vary from mild to life-threatening, where severe illness is often …

A complex intracellular signaling governs different cellular responses in inflammation.
Extracellular stimuli are sensed, amplified, and transduced through a dynamic cellular …

Inflammation is an essential mechanism of various diseases. The development and
resolution of inflammation are complex immune-modulation processes which induce the …

Timely resolution of bacterial infections critically depends on phagocytosis of invading
pathogens by polymorphonuclear neutrophil granulocytes (PMNs), followed by PMN …

Coronavirus disease (COVID)-19, as a result of Severe Acute Respiratory Syndrome
Coronavirus 2 (SARS-CoV-2) infection, has been the direct cause of over 2.2 million deaths …

During an infection, inflammation mobilizes immune cells to eliminate the pathogen and
protect the host. However, inflammation can be detrimental when exacerbated and/or …