The brain lacks a classic lymphatic drainage system. How it is cleansed of damaged
proteins, cellular debris, and molecular by-products has remained a mystery for decades …

The current understanding of neurological diseases is derived mostly from direct analysis of
patients and from animal models of disease. However, most patient studies do not capture …

The size of the cerebral cortex increases dramatically across amniotes, from reptiles to great
apes. This is primarily due to different numbers of neurons and glial cells produced during …

During central nervous system (CNS) development, neural progenitor cells (NPCs) generate
neurons and glia in two different ways. In direct neurogenesis, daughter cells differentiate …

Neural stem cells (NSCs), an invaluable source of neuronal and glial progeny, have been
widely interrogated in the last twenty years, mainly to understand their therapeutic potential …

Abstract Background/Objective. Enlarged lateral ventricle (LV) volume and decreased
volume in the corpus callosum (CC) are hallmarks of schizophrenia (SZ). We previously …

Exercise improves cognitive function in Alzheimer's Disease (AD), via mechanism that are
not fully clear. Here, we first examined the effect of voluntary exercise training (VET) on …

The evolutionary emergence of the corticospinal tract and corpus callosum are thought to
underpin the expansion of complex motor and cognitive abilities in mammals. Molecular …

Different neuron types develop characteristic axonal and dendritic arborizations that
determine their inputs, outputs, and functions. Expression of fate-determinant transcription …

Traumatic brain injury (TBI) is a significant risk factor for neurodegenerative disorders, and
patients often experience varying degrees of motor impairment. MiR-137, a broadly …