Objectives: A significant body of knowledge implicates menopausal estrogen levels in the
pathogenesis of the common pelvic floor disorders (PFDs). These health conditions …

Aims To determine the effects of oestrogen or oestrogen deprivation on vaginal wound
healing. Impaired wound healing following prolapse surgery may increase the risk of …

Understanding the microflora inhabiting the reproductive tract is important for a better
understanding of female physiology and reproductive health. The endometrial fluid from …

Loss of estrogen as a result of aging, pelvic cancer therapy, genetics, or eating disorders
affects numerous body systems including the reproductive tract. Specifically, a chronic …

Pelvic organ prolapse (POP) is common among post-menopausal women and is associated
with bladder, bowel, and sexual dysfunction. Surgical repair with the patients' native tissues …

Pelvic organ prolapse, a condition in which the pelvic organs drop into the vagina causing
pressure and discomfort, is a highly prevalent condition that confers a 12.6% lifetime risk of …

Progress toward understanding the underlying mechanisms of pelvic organ prolapse (POP)
is limited, in part, due to a lack of information on the biomechanical properties and …

Objectives The aim of this study was to evaluate the effectiveness of modified McCall
culdoplasty or Shull suspension in preventing vaginal vault prolapse after vaginal …

Objective: To design and validate a novel murine model of full-thickness (FT) vaginal wound
healing that mirrors postinjury tissue repair and underscores the impact of estrogen …

Background & objectives Vaginal atrophy is characterized by thinning of vaginal epithelial
layers and decreased local blood flow. We aimed to evaluate the regenerative effects of …