Tissue damage thresholds during therapeutic electrical stimulation
Objective. Recent initiatives in bioelectronic modulation of the nervous system by the NIH
(SPARC), DARPA (ElectRx, SUBNETS) and the GlaxoSmithKline Bioelectronic Medicines …
(SPARC), DARPA (ElectRx, SUBNETS) and the GlaxoSmithKline Bioelectronic Medicines …
[HTML][HTML] Closed-loop brain stimulation for drug-resistant epilepsy: towards an evidence-based approach to personalized medicine
Closed-loop brain stimulation is one of the few treatments available for patients who are
ineligible for traditional surgical resection of the epileptogenic zone, due to having …
ineligible for traditional surgical resection of the epileptogenic zone, due to having …
Long-term brain network reorganization predicts responsive neurostimulation outcomes for focal epilepsy
AN Khambhati, A Shafi, VR Rao… - Science Translational …, 2021 - science.org
Responsive neurostimulation (RNS) devices, able to detect imminent seizures and to rapidly
deliver electrical stimulation to the brain, are effective in reducing seizures in some patients …
deliver electrical stimulation to the brain, are effective in reducing seizures in some patients …
Systems and methods for tissue stimulation in medical treatment
MS John - US Patent 8,788,044, 2014 - Google Patents
Stimulation treatments for various medical disorders, such as neurological disorders,
comprise novel systems, strategies, and methods for providing TMS, electrical, magnetic …
comprise novel systems, strategies, and methods for providing TMS, electrical, magnetic …
Multiple-symptom medical treatment with roving-based neurostimulation
JS John - US Patent 8,825,166, 2014 - Google Patents
Stimulation treatments for various medical disorders com prise serially varying the
stimulation parameters, especially in order to treat multiple symptoms of a disorder. Roving …
stimulation parameters, especially in order to treat multiple symptoms of a disorder. Roving …
Association of closed-loop brain stimulation neurophysiological features with seizure control among patients with focal epilepsy
Importance A bidirectional brain-computer interface that performs neurostimulation has been
shown to improve seizure control in patients with refractory epilepsy, but the therapeutic …
shown to improve seizure control in patients with refractory epilepsy, but the therapeutic …
Responsive neurostimulation with low‐frequency stimulation
Deep brain stimulation and responsive neurostimulation (RNS) use high‐frequency
stimulation (HFS) per the pivotal trials and manufacturer‐recommended therapy protocols …
stimulation (HFS) per the pivotal trials and manufacturer‐recommended therapy protocols …
Critical review of the responsive neurostimulator system for epilepsy
GP Thomas, BC Jobst - Medical Devices: Evidence and Research, 2015 - Taylor & Francis
Patients with medically refractory epilepsy have historically had few effective treatment
options. Electrical brain stimulation for seizures has been studied for decades and ongoing …
options. Electrical brain stimulation for seizures has been studied for decades and ongoing …
Chronic subdural electrodes in the management of epilepsy
Subdural electrodes play a very important role in the evaluation of a percentage of patients
being considered for epilepsy surgery. Electrical activity at very low and very high …
being considered for epilepsy surgery. Electrical activity at very low and very high …
Cellular mechanisms underlying antiepileptic effects of low-and high-frequency electrical stimulation in acute epilepsy in neocortical brain slices in vitro
Y Schiller, Y Bankirer - Journal of neurophysiology, 2007 - journals.physiology.org
Approximately 30% of epilepsy patients suffer from drug-resistant epilepsy. Direct electrical
stimulation of the epileptogenic zone is a potential new treatment modality for this …
stimulation of the epileptogenic zone is a potential new treatment modality for this …