Trace amines and their receptors

RR Gainetdinov, MC Hoener, MD Berry… - Pharmacological …, 2018 - Elsevier
Trace amines are endogenous compounds classically regarded as comprising β-
phenylethyalmine, p-tyramine, tryptamine, p-octopamine, and some of their metabolites …

Screening for fetal growth restriction and placental insufficiency

MC Audette, JC Kingdom - Seminars in Fetal and Neonatal Medicine, 2018 - Elsevier
Fetal growth restriction (FGR) continues to be a leading cause of preventable stillbirth and
poor neurodevelopmental outcomes in offspring, and furthermore is strongly associated with …

[HTML][HTML] Formate metabolism in health and disease

M Pietzke, J Meiser, A Vazquez - Molecular metabolism, 2020 - Elsevier
Background Formate is a one-carbon molecule at the crossroad between cellular and whole
body metabolism, between host and microbiome metabolism, and between nutrition and …

Balancing the Equation: A Natural History of Trimethylamine and Trimethylamine-N-oxide

RL Loo, Q Chan, JK Nicholson… - Journal of Proteome …, 2022 - ACS Publications
Trimethylamine (TMA) and its N-oxide (TMAO) are ubiquitous in prokaryote and eukaryote
organisms as well as in the environment, reflecting their fundamental importance in …

Diurnal rhythms in the human urine metabolome during sleep and total sleep deprivation

GF Giskeødegård, SK Davies, VL Revell, H Keun… - Scientific reports, 2015 - nature.com
Understanding how metabolite levels change over the 24 hour day is of crucial importance
for clinical and epidemiological studies. Additionally, the association between sleep …

Cohort profile: the mother-child cohort in Crete, Greece (Rhea Study)

L Chatzi, V Leventakou, M Vafeiadi… - International journal …, 2017 - academic.oup.com
Epidemiological and animal research shows that disease aetiology often has to be
evaluated with a life course perspective, starting as close to the time of conception as …

Beyond genomics: understanding exposotypes through metabolomics

NJW Rattray, NC Deziel, JD Wallach, SA Khan… - Human genomics, 2018 - Springer
Background Over the past 20 years, advances in genomic technology have enabled
unparalleled access to the information contained within the human genome. However, the …

Molecular mechanism of microbiota metabolites in preterm birth: pathological and therapeutic insights

AZ Ansari, S Bose, Y You, S Park, Y Kim - International Journal of …, 2021 - mdpi.com
Preterm birth (PTB) refers to the birth of infants before 37 weeks of gestation and is a
challenging issue worldwide. Evidence reveals that PTB is a multifactorial dysregulation …

The complex metabolism of trimethylamine in humans: endogenous and exogenous sources

J Chhibber-Goel, A Gaur, V Singhal… - Expert Reviews in …, 2016 - cambridge.org
Trimethylamine (TMA) is a tertiary amine with a characteristic fishy odour. It is synthesised
from dietary constituents, including choline, L-carnitine, betaine and lecithin by the action of …

Metabolomic signatures associated with fetal growth restriction and small for gestational age: a systematic review

A Conde-Agudelo, J Villar, M Risso… - Nature …, 2024 - nature.com
The pathways involved in the pathophysiology of fetal growth restriction (FGR) and small for
gestational age (SGA) are incompletely understood. We conduct a systematic review to …