Bone tissue engineering is becoming an ideal strategy to replace autologous bone grafts for
surgical bone repair, but the multihierarchical complexity of natural bone is still difficult to …

There is growing evidence that mesenchymal stem cell-derived extracellular vesicles and
exosomes can significantly improve the curative effect of oxidative stress-related diseases …

Aims Naturally secreted extracellular vesicles (EVs) play important roles in stem-mediated
cardioprotection. This study aimed to investigate the cardioprotective function and …

Molecular self-assembly has forged a new era in the development of advanced biomaterials
for local drug delivery and tissue engineering applications. Given their innate …

Fibrosis is the unrelenting deposition of excessively large amounts of insoluble interstitial
collagen due to profound matrigenic activities of wound-associated myofibroblasts during …

Extracellular vesicle (EV)-based therapies have been successfully tested in preclinical
models for several biomedical applications, including tissue engineering, drug delivery and …

Immunomodulation is on the cusp of being an important therapy for treating many diseases,
due to the significant role of the immune system in defending the human body. Although the …

Over the past two decades, mesenchymal stromal cells (MSCs) have demonstrated great
potential in the treatment of inflammation-related conditions. Numerous early stage clinical …

Exosomes are extracellular vesicles which carry specific molecular information from donor
cells and act as an intercellular communication vehicle, which have emerged as a novel cell …

Myocardial infarction is one of the major causes of morbidity and mortality worldwide.
Current treatments can relieve the symptoms of myocardial ischemia but cannot repair the …