B cells are typically characterized by their ability to produce antibodies, function as
secondary antigen-present cells, and produce various immunoregulatory cytokines. The …

The administration of T cells that have been modified to carry chimeric antigen receptors
(CARs) aimed at B cells has been an effective strategy in treating B cell malignancies. This …

The complex nature of the innate lymphoid cell (ILC) family and wide range of ILC effector
functions has been the focus of intense research. In addition to important roles in host …

Aging is associated with a decline in immune function, thereby causing an increased
susceptibility to various diseases. Herein, we review immune diseases associated with …

Cellular immunotherapy represents a pivotal treatment modality in clinical practice.
Regulatory B cells (Bregs), a key subset of B lymphocytes, hold promise in the management …

Immune thrombocytopenia (ITP) is an autoimmune-mediated disease characterized by
decreased platelet counts. Cytokines play important roles in modulating the immune …

Forkhead box O3 (FOXO3) is a transcription factor involved in cell metabolism, survival,
longevity and inflammatory diseases. In the current thesis, we provided evidence that …

Factors regulating T cell and innate lymphoid cell (ILC) cross-talk ensure coordinated
immune responses. Human leukocyte antigen-B-associated transcript 3 (Bat3) protects T …

Актуальным трендом в исследованиях В-клеточного звена иммунной системы является
изучение малых субпопуляций. Установлено, что минорная субпопуляция IL-10 …

The current trend in studies of the B-cell immunity is the study of small subpopulations of
cells. It was found that a minor subpopulation of IL-10 producing B-cells (B10-reg cells) has …