Most of the drugs and pharmacologically relevant molecules possess heterocyclic ring
structures and presence of hetero atoms or groupings divulges privileged specificities in …

Emergence of drug resistance has created unmet medical need for the development of new
classes of antibiotics. Discovery of new antibacterial agents with new mode of action …

A novel series of substituted 4, 6-dimethyl-2-oxo-1-(thiazol-2-ylamino)-1, 2-dihydropyridine-
3-carbonitrile derivatives 6, 9, 13, 15, and 17 was synthesized in a good to excellent yield …

There is an urgent need for the discovery and development of new antitubercular agents that
target new biochemical pathways and treat drug resistant forms of the disease. One …

Coronavirus disease 2019 (COVID-19) is a fatal respiratory illness caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2). The identification of potential drugs is …

A novel palladium-catalyzed three-component reaction for the synthesis of quinazolin-4 (3
H)-ones from readily available 2-aminobenzamides and aryl halides via a palladium …

A series of novel 4-thioquinazoline derivatives containing chalcone moiety were designed,
synthesized and systematically evaluated for their antiviral activity against TMV. The …

There is an urgent need for the discovery and development of new antitubercular agents that
target novel biochemical pathways and treat drug-resistant forms of the disease. One …

Artemisinin is a natural compound extracted from Artemisia species belonging to the
Asteraceae family. Currently, artemisinin and its derivatives are considered among the most …

Conclusion Quinazoline derivatives are the emerging pharmacophore which has drawn a
growing interest in the arena of drug designing. In last year, about hundred publications …