Carcinoma, characterized by abnormal growth of cells and tissue, is a ubiquitously leading
cause of mortality across the globe due to some carcinogenic factors. Currently, several …

1, 2, 4-Oxadiazole is an essential motif in drug discovery represented in many experimental,
investigational, and marketed drugs. This review covers synthetic methods that allow the …

This review is focused on the synthetic strategies to heterocyclic C-nucleosides and covers
the literature from 2011 to 2021. The main attention is paid to the following three …

The close association between inflammation and cancer inspired the synthesis of a series of
1, 3, 4‐oxadiazole derivatives (compounds H4‐A‐F) of 6‐methoxynaphtalene. The chemical …

Triazoles and tetrazoles are biologically significant five-membered heterocyclic that
constitute the skeletons of several commercially marketed drugs and other heterocyclic …

Scalable synthesis of amidoxime 1 by nucleophilic addition of 50% aq. NH2OH to 3-
hydroxypropionitrile is reported. In the presence of hydroxyl and amidoxime moieties, this …

Five membered oxa-and thiadiazole derivatives have shown significant biological activity
due to their unique bioisosteric properties. Herein, we describe an efficient synthetic …

Triazoles and tetrazoles are the biologically significant five-membered heterocycles
constituting the skeletons of several commercially marketed drugs and other heterocyclic …

A concise synthesis of 2'-deoxyisoguanosine is achieved whereby 2, 6-dichloropurine is
glycosylated using the Hoffer sugar to give a pair of beta-configured nucleoside N9/N7 …

Исследованы различные подходы к синтезу 3-галогенпиразоло [1, 5-a] пиримидинов.
Установлено, что наиболее эффективным методом является построение …