Endoperoxidases in biosynthesis of endoperoxide bonds

S Zhang, B He, A Qu-Bie, M Li, M Luo, M Feng… - International Journal of …, 2024 - Elsevier
Endoperoxides are important sources of ideas for drug discovery. Endoperoxide bonds are
considered to be the cause of the interesting biological activities of endoperoxides, but there …

Recent advances in the synthesis and antimalarial activity of 1, 2, 4-trioxanes

K Rathi, M Shukla, M Hassam, R Shrivastava… - Bioorganic …, 2024 - Elsevier
The increasing resistance of various malarial parasite strains to drugs has made the
production of a new, rapid-acting, and efficient antimalarial drug more necessary, as the …

Design, Synthesis, Molecular Docking, Drug-Likeness/ADMET and Molecular Dynamics Studies of Thiazolyl Benzenesulfonamide Carboxylates as Antimalarial …

JA Ezugwu, UC Okoro, MA Ezeokonkwo… - Chemistry Africa, 2024 - Springer
In this work, nine novel thiazole derivatives of substituted benzenesulfonamide carboxylate
were designed, synthesized and characterized (1H NMR, 13C NMR and Mass Spectra) for …

Novel amino-and hydroxy-functionalized 1, 2, 4-trioxanes and their antimalarial activity against multidrug-resistant Plasmodium yoelii nigeriensis in Swiss mice via …

P Yadav, NK Naikade, M Hassam, AS Singh… - Bioorganic & Medicinal …, 2024 - Elsevier
Following the economic and social state of humanity, Malaria is categorized as one of the
life-threatening illness epidemics in under developed countries. For the eradication of the …

Novel saturated 1, 2, 4-trioxanes and their antimalarial activity against multidrug resistant Plasmodium yoelii nigeriensis in Swiss mice model via oral route

A Kumari, P Yadav, V Rawat, RA Maurya… - Bioorganic & Medicinal …, 2024 - Elsevier
Abstract Novel saturated 6-(4′-aryloxy phenyl) vinyl 1, 2, 4-trioxanes 12a (1–3)–12d (1–3)
and 13a (1–3)–13d (1–3) have been designed and synthesized, in one single step from …

[PDF][PDF] Formulation and characterization of GDL-based artesunate solid lipid nanoparticle

A JAIN, SP Vyas - Int J App Pharm, 2023 - academia.edu
Objective: The present research aimed to prepare and characterize glyceryl dilaurate (GDL)
containing solid lipid nanoparticles (SLN) with tween 80 and lecithin as an emulsifier in …

[PDF][PDF] GC-MS Profile of Ethanolic Root Extract of Withania somnifera (Ashwagandha)

N Singh - researchgate.net
In the present study phyto-constituents of root ethanolic extract were analyzed to check and
identify the important phytochemicals by GCMS analysis. The present study indicates the …

Synthesis of Ozonides Mediated by Molecular Sieve Under Solvent-Free Conditions

N Kishimoto, K Tanaka, H Takamura… - Available at SSRN … - papers.ssrn.com
An efficient method for the direct synthesis of ozonides via the reaction of alkenes with an
ozone stream under solvent-free conditions is described. In this study, the alkene substrates …