Use of molecular docking computational tools in drug discovery
F Stanzione, I Giangreco, JC Cole - Progress in medicinal chemistry, 2021 - Elsevier
Molecular docking has become an important component of the drug discovery process.
Since first being developed in the 1980s, advancements in the power of computer hardware …
Since first being developed in the 1980s, advancements in the power of computer hardware …
[HTML][HTML] Artificial intelligence for COVID-19: a systematic review
L Wang, Y Zhang, D Wang, X Tong, T Liu… - Frontiers in …, 2021 - frontiersin.org
Background: Recently, Coronavirus Disease 2019 (COVID-19), caused by severe acute
respiratory syndrome virus 2 (SARS-CoV-2), has affected more than 200 countries and lead …
respiratory syndrome virus 2 (SARS-CoV-2), has affected more than 200 countries and lead …
Potential SARS-CoV-2 main protease inhibitors
R Banerjee, L Perera, LMV Tillekeratne - Drug Discovery Today, 2021 - Elsevier
Highlights•The SARS-CoV-2 main protease is a prime drug target.•Coronavirus main
proteases share a structurally conserved substrate-binding region.•The structure and …
proteases share a structurally conserved substrate-binding region.•The structure and …
A review on drug repurposing applicable to COVID-19
S Dotolo, A Marabotti, A Facchiano… - Briefings in …, 2021 - academic.oup.com
Drug repurposing involves the identification of new applications for existing drugs at a lower
cost and in a shorter time. There are different computational drug-repurposing strategies and …
cost and in a shorter time. There are different computational drug-repurposing strategies and …
Drugs targeting various stages of the SARS-CoV-2 life cycle: Exploring promising drugs for the treatment of Covid-19
R Poduri, G Joshi, G Jagadeesh - Cellular signalling, 2020 - Elsevier
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a positive-sense,
single-stranded RNA virus that causes the potentially lethal Covid-19 respiratory tract …
single-stranded RNA virus that causes the potentially lethal Covid-19 respiratory tract …
Pharmacological therapeutics targeting RNA-dependent RNA polymerase, proteinase and spike protein: from mechanistic studies to clinical trials for COVID-19
An outbreak of novel coronavirus-related pneumonia COVID-19, that was identified in
December 2019, has expanded rapidly, with cases now confirmed in more than 211 …
December 2019, has expanded rapidly, with cases now confirmed in more than 211 …
Progress in developing inhibitors of SARS-CoV-2 3C-like protease
Q Li, CB Kang - Microorganisms, 2020 - mdpi.com
Coronavirus disease 2019 (COVID-19) is caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2). The viral outbreak started in late 2019 and rapidly became a …
coronavirus 2 (SARS-CoV-2). The viral outbreak started in late 2019 and rapidly became a …
[HTML][HTML] The spike glycoprotein of SARS-CoV-2: A review of how mutations of spike glycoproteins have driven the emergence of variants with high transmissibility and …
Abstract Late in 2019, SARS-CoV-2 (severe acute respiratory syndrome coronavirus-2)
emerged, causing an unknown type of pneumonia today called coronaviruses disease 2019 …
emerged, causing an unknown type of pneumonia today called coronaviruses disease 2019 …
Drug targets for COVID-19 therapeutics: Ongoing global efforts
A Saxena - Journal of biosciences, 2020 - Springer
The current global pandemic COVID-19 caused by the SARS-CoV-2 virus has already
inflicted insurmountable damage both to the human lives and global economy. There is an …
inflicted insurmountable damage both to the human lives and global economy. There is an …
[HTML][HTML] Recent advances in developing small-molecule inhibitors against SARS-CoV-2
R Xiang, Z Yu, Y Wang, L Wang, S Huo, Y Li… - … Pharmaceutica Sinica B, 2022 - Elsevier
The COVID-19 pandemic caused by the novel SARS-CoV-2 virus has caused havoc across
the entire world. Even though several COVID-19 vaccines are currently in distribution …
the entire world. Even though several COVID-19 vaccines are currently in distribution …