Abstract Background. The DNA Mismatch repair (MMR) system is a highly preserved protein
complex recognizing short insertions, short deletions and single base mismatches during …

Due to predictions of increasing incidences and deaths from ovarian cancer, this neoplasm
is a challenge for modern health care. The advent of NGS technology has made it possible …

The comparative analysis of the expression of the reactive oxygen species-generating
NADPH oxidase NOX4 from TCGA data shows that the NOX4 transcript is upregulated in …

The hypermethylation status of the promoter region of the breast cancer 1 (BRCA1), a well-
known tumor suppressor gene, has been extensively investigated in the last two decades as …

Mismatch repair/microsatellite instability (MMR/MSI) status in colorectal cancer (CRC) has
become fundamental as a diagnostic, prognostic, and predictive factor. MMR …

Simple Summary In our study, we found genetic mutations in the DNA of cancer cells
obtained from the blood of many patients with metastatic prostate cancer. These changes …

The molecular characterization of soft tissue and bone tumors is a rapidly evolving field that
has changed the perspective of how these tumors are diagnosed today. Morphology and …

Microorganisms have been identified in tumor specimens for over a century. It is only in
recent years that tumor-associated microbiota has become a rapidly expanding field …

Recent breakthroughs in cancer immunotherapies have emphasized the importance of
harnessing the immune system for treating cancer. Vaccines, which have traditionally been …

GNAS-activating somatic mutations give rise to Fibrous Dysplasia/McCune–Albright
syndrome (FD/MAS). The low specificity of extra-skeletal signs of MAS and the mosaic status …