From patterns to patients: Advances in clinical machine learning for cancer diagnosis, prognosis, and treatment

K Swanson, E Wu, A Zhang, AA Alizadeh, J Zou - Cell, 2023 - cell.com
Machine learning (ML) is increasingly used in clinical oncology to diagnose cancers, predict
patient outcomes, and inform treatment planning. Here, we review recent applications of ML …

Early detection of cancer

D Crosby, S Bhatia, KM Brindle, LM Coussens, C Dive… - Science, 2022 - science.org
Survival improves when cancer is detected early. However,~ 50% of cancers are at an
advanced stage when diagnosed. Early detection of cancer or precancerous change allows …

Liquid biopsy enters the clinic—implementation issues and future challenges

M Ignatiadis, GW Sledge, SS Jeffrey - Nature reviews Clinical oncology, 2021 - nature.com
Historically, studies of disseminated tumour cells in bone marrow and circulating tumour
cells in peripheral blood have provided crucial insights into cancer biology and the …

[HTML][HTML] Machine learning-based approach: Global trends, research directions, and regulatory standpoints

R Pugliese, S Regondi, R Marini - Data Science and Management, 2021 - Elsevier
The field of machine learning (ML) is sufficiently young that it is still expanding at an
accelerating pace, lying at the crossroads of computer science and statistics, and at the core …

Clinical applications of artificial intelligence and machine learning in cancer diagnosis: looking into the future

MJ Iqbal, Z Javed, H Sadia, IA Qureshi, A Irshad… - Cancer cell …, 2021 - Springer
Artificial intelligence (AI) is the use of mathematical algorithms to mimic human cognitive
abilities and to address difficult healthcare challenges including complex biological …

Cell-free DNA analysis in current cancer clinical trials: a review

M Cisneros-Villanueva, L Hidalgo-Pérez… - British journal of …, 2022 - nature.com
Cell-free DNA (cfDNA) analysis represents a promising method for the diagnosis, treatment
selection and clinical follow-up of cancer patients. Although its general methodological …

Bridging biological cfDNA features and machine learning approaches

T Moser, S Kühberger, I Lazzeri, G Vlachos, E Heitzer - Trends in Genetics, 2023 - cell.com
Liquid biopsies (LBs), particularly using circulating tumor DNA (ctDNA), are expected to
revolutionize precision oncology and blood-based cancer screening. Recent technological …

Artificial intelligence in colorectal cancer screening, diagnosis and treatment. A new era

A Mitsala, C Tsalikidis, M Pitiakoudis, C Simopoulos… - Current …, 2021 - mdpi.com
The development of artificial intelligence (AI) algorithms has permeated the medical field
with great success. The widespread use of AI technology in diagnosing and treating several …

Salivary MicroRNA signature for diagnosis of endometriosis

S Bendifallah, S Suisse, A Puchar, L Delbos… - Journal of clinical …, 2022 - mdpi.com
Background: Endometriosis diagnosis constitutes a considerable economic burden for the
healthcare system with diagnostic tools often inconclusive with insufficient accuracy. We …

Toward the early detection of cancer by decoding the epigenetic and environmental fingerprints of cell-free DNA

Y Van Der Pol, F Mouliere - Cancer cell, 2019 - cell.com
Widespread adaptation of liquid biopsy for the early detection of cancer has yet to reach
clinical utility. Circulating tumor DNA is commonly detected though the presence of genetic …