NLR family pyrin domain containing 3 (NLRP3) inflammasomes and peripheral neuropathic pain-Emphasis on microRNAs (miRNAs) as important regulators

P Basu, C Maier, DL Averitt, A Basu - European Journal of Pharmacology, 2023 - Elsevier
Neuropathic pain is caused by the lesion or disease of the somatosensory system and can
be initiated and/or maintained by both central and peripheral mechanisms. Nerve injury …

MicroRNAs in the spinal microglia serve critical roles in neuropathic pain

S Tang, H Jing, F Song, H Huang, W Li, G Xie… - Molecular …, 2021 - Springer
Neuropathic pain (NP) can occur after peripheral nerve injury (PNI), and it can be converted
into a maladaptive, detrimental phenotype that causes a long-term state of pain …

[HTML][HTML] Myostatin and CXCL11 promote nervous tissue macrophages to maintain osteoarthritis pain

CM Gil, R Raoof, S Versteeg, HLDM Willemen… - Brain, Behavior, and …, 2024 - Elsevier
Pain is the most debilitating symptom of knee osteoarthritis (OA) that can even persist after
total knee replacement. The severity and duration of pain do not correlate well with joint …

Simultaneous activation of mu and delta opioid receptors reduces allodynia and astrocytic connexin 43 in an animal model of neuropathic pain

N Vicario, L Pasquinucci, FM Spitale, S Chiechio… - Molecular …, 2019 - Springer
Neuropathic pain is a chronic condition triggered by lesions to the somatosensory nervous
system in which pain stimuli occur spontaneously or as pathologically amplified responses …

[HTML][HTML] Regulation by noncoding RNAs of local translation, injury responses, and pain in the peripheral nervous system

X Li, DS Jin, S Eadara, MJ Caterina, MK Meffert - Neurobiology of Pain, 2023 - Elsevier
Neuropathic pain is a chronic condition arising from damage to somatosensory pathways
that results in pathological hypersensitivity. Persistent pain can be viewed as a …

Exosome theranostics: comparative analysis of P body and exosome proteins and their mutations for clinical applications

G Satheeshan, AK Si, J Rutta, T Venkatesh - Functional & Integrative …, 2024 - Springer
Exosomes are lipid-bilayered vesicles, originating from early endosomes that capture
cellular proteins and genetic materials to form multi-vesicular bodies. These exosomes are …

Infiltrated Macrophages Aggravate TMJOA Chronic Pain Via Piezo2 in IB4 -TG Neurons

X Jia, X Liu, T Zhu, X Ma, R Chen, H Li, Y Feng… - 2024 - papers.ssrn.com
Temporomandibular joint osteoarthritis (TMJOA) chronic pain is one of the orofacial pains
that result in limitations in chewing function and a decline in quality of life. Currently …