Skeletal muscle is the most abundant tissue in healthy individuals and it has important roles
in health beyond voluntary movement. The overall mass and energy requirements of …

Skeletal muscle myosin heavy chain (MyHC) fiber type composition is a critical determinant
of overall muscle function and health. Various approaches interrogate fiber type at the single …

Satellite cell-mediated myonuclear accretion is thought to be required for skeletal muscle
fiber hypertrophy, and even drive hypertrophy by preceding growth. Recent studies in …

The Exercise Boom of the 1970's resulted in the adoption of habitual exercise in a significant
portion of the population. Many of these individuals are defying the cultural norms by …

The efficacy of the NASA SPRINT exercise countermeasures program for quadriceps (vastus
lateralis) and triceps surae (soleus) skeletal muscle health was investigated during 70 days …

Skeletal muscle disuse results in rapid functional declines. Previous studies have typically
been at least 1 week in duration and focused on the responsiveness of men. Herein, we …

The physiological challenges presented by space flight and in microgravity (μG)
environments are well documented. μG environments can result in declines muscle mass …

Prolonged periods in microgravity (μG) environments result in deconditioning of numerous
physiological systems, particularly muscle at molecular, single fiber, and whole muscle …

Key points A hallmark trait of ageing skeletal muscle health is a reduction in size and
function, which is most pronounced in the fast muscle fibres. We studied older men (74±4 …

We previously observed a range of whole muscle and individual slow and fast myofiber size
responses (mean:+ 4 to− 24%) in quadriceps (vastus lateralis) and triceps surae (soleus) …