A review of single-cell adhesion force kinetics and applications

A Shinde, K Illath, P Gupta, P Shinde, KT Lim, M Nagai… - Cells, 2021 - mdpi.com
Cells exert, sense, and respond to the different physical forces through diverse mechanisms
and translating them into biochemical signals. The adhesion of cells is crucial in various …

Current trends of microfluidic single-cell technologies

P Shinde, L Mohan, A Kumar, K Dey, A Maddi… - International journal of …, 2018 - mdpi.com
The investigation of human disease mechanisms is difficult due to the heterogeneity in gene
expression and the physiological state of cells in a given population. In comparison to bulk …

Nanoscale tweezers for single-cell biopsies

BP Nadappuram, P Cadinu, A Barik… - Nature …, 2019 - nature.com
Much of the functionality of multicellular systems arises from the spatial organization and
dynamic behaviours within and between cells. Current single-cell genomic methods only …

Near-infrared nanosecond-pulsed laser-activated highly efficient intracellular delivery mediated by nano-corrugated mushroom-shaped gold-coated polystyrene …

TS Santra, S Kar, TC Chen, CW Chen, J Borana… - Nanoscale, 2020 - pubs.rsc.org
Here, an efficient intracellular delivery of molecules with high cell viability is reported using
nanosecond-pulsed laser-activated plasmonic photoporation, mediated by high-aspect-ratio …

Single-cell electroporation: current trends, applications and future prospects

S Kar, M Loganathan, K Dey, P Shinde… - Journal of …, 2018 - iopscience.iop.org
The ability to deliver foreign molecules into a single living cell with high transfection
efficiency and high cell viability is of great interest in cell biology for applications in …

Metallic micro-ring device for highly efficient large cargo delivery in mammalian cells using infrared light pulses

A Shinde, P Shinde, S Kar, K Illath, S Dey… - Lab on a Chip, 2023 - pubs.rsc.org
Uniform transfection of biomolecules into live cells with high delivery efficiency and cell
viability is an immensely important area of biological research and has many biomedical …

Nano-localized single-cell nano-electroporation

TS Santra, S Kar, HY Chang, FG Tseng - Lab on a Chip, 2020 - pubs.rsc.org
The ability to deliver foreign cargos into single living cells is of great interest in cell biology
and therapeutic research. Here, we have reported a single or multiple position based nano …

Infrared pulse laser-activated highly efficient intracellular delivery using titanium microdish device

P Shinde, S Kar, M Loganathan… - ACS Biomaterials …, 2020 - ACS Publications
We report infrared (IR) pulse laser-activated highly efficient parallel intracellular delivery by
using an array of titanium microdish (TMD) device. Upon IR laser pulse irradiation, a two …

Characterization of cytoplasmic viscosity of hundreds of single tumour cells based on micropipette aspiration

K Wang, XH Sun, Y Zhang, T Zhang… - Royal Society …, 2019 - royalsocietypublishing.org
Cytoplasmic viscosity (μ c) is a key biomechanical parameter for evaluating the status of
cellular cytoskeletons. Previous studies focused on white blood cells, but the data of …

Scaling and automation of a high-throughput single-cell-derived tumor sphere assay chip

YH Cheng, YC Chen, R Brien, E Yoon - Lab on a Chip, 2016 - pubs.rsc.org
Recent research suggests that cancer stem-like cells (CSCs) are the key subpopulation for
tumor relapse and metastasis. Due to cancer plasticity in surface antigen and enzymatic …