Severe asthma in children is rare, accounting for only a small proportion of childhood
asthma. After addressing modifiable factors such as adherence to treatment, comorbidities …

Severe asthma often remains uncontrolled despite effective treatments and evidence-based
guidelines. A group of global experts in asthma and biologic medications from 9 countries …

In the pathogenesis of asthma in children there is a pivotal role for a type 2 inflammatory
response to early life exposures or events. Interactions between infections, atopy, genetic …

Asthma is a highly heterogeneous disease, often manifesting with wheeze, dyspnea, chest
tightness, and cough as prominent symptoms. The eliciting factors, natural history …

Background The effects of omalizumab on food allergy thresholds have been little studied.
Objective To assess the real-life effects of omalizumab on food threshold tolerability in …

Asthma is a common chronic inflammatory disorder of the lower respiratory airways in
childhood. The management of asthma exacerbations and the disease control are major …

Introduction: Omalizumab is a recombinant monoclonal anti-IgE antibody approved in the
US as add-on treatment in moderate-to-severe allergic asthma (in severe allergic asthma …

Severe asthma is a relatively uncommon condition in children but one which causes
morbidity, occasionally mortality, and is a challenging condition to manage. There are …

The advent of personalized medicine has revolutionized the whole approach to the
management of asthma, representing the essential basis for future developments. The …

Known to have affected around 340 million people across the world in 2018, asthma is a
prevalent chronic inflammatory disease of the airways. The symptoms such as wheezing …