Noncoding RNAs in gastric cancer: implications for drug resistance

L Wei, J Sun, N Zhang, Y Zheng, X Wang, L Lv, J Liu… - Molecular cancer, 2020 - Springer
Gastric cancer is the fourth most common malignancy and the third leading cause of cancer-
related deaths worldwide. Advanced gastric cancer patients can notably benefit from …

The emerging role of the piRNA/piwi complex in cancer

Y Liu, M Dou, X Song, Y Dong, S Liu, H Liu, J Tao, W Li… - Molecular cancer, 2019 - Springer
Piwi interacting RNAs (piRNAs) constitute novel small non-coding RNA molecules of
approximately 24–31 nucleotides in length that often bind to members of the piwi protein …

Role of non-coding RNAs and RNA modifiers in cancer therapy resistance

X Zhang, K Xie, H Zhou, Y Wu, C Li, Y Liu, Z Liu, Q Xu… - Molecular cancer, 2020 - Springer
As the standard treatments for cancer, chemotherapy and radiotherapy have been widely
applied to clinical practice worldwide. However, the resistance to cancer therapies is a major …

[HTML][HTML] Non-coding RNA in cancer drug resistance: Underlying mechanisms and clinical applications

X Zhou, X Ao, Z Jia, Y Li, S Kuang, C Du… - Frontiers in …, 2022 - frontiersin.org
Cancer is one of the most frequently diagnosed malignant diseases worldwide, posing a
serious, long-term threat to patients' health and life. Systemic chemotherapy remains the first …

The emerging role of microRNAs and long noncoding RNAs in drug resistance of hepatocellular carcinoma

L Wei, X Wang, L Lv, J Liu, H Xing, Y Song, M Xie… - Molecular Cancer, 2019 - Springer
Hepatocellular carcinoma (HCC) is the fifth most common malignancy worldwide and the
second most lethal human cancer. A portion of patients with advanced HCC can significantly …

Inflammatory cytokine–regulated tRNA-derived fragment tRF-21 suppresses pancreatic ductal adenocarcinoma progression

L Pan, X Huang, ZX Liu, Y Ye, R Li… - The Journal of …, 2021 - Am Soc Clin Investig
The tumorigenic mechanism for pancreatic ductal adenocarcinoma (PDAC) is not clear,
although chronic inflammation is implicated. Here, we identified an inflammatory cytokine …

LncRNA CACClnc promotes chemoresistance of colorectal cancer by modulating alternative splicing of RAD51

X Zhang, D Ma, B Xuan, D Shi, J He, M Yu, H Xiong… - Oncogene, 2023 - nature.com
Long non-coding RNAs (lncRNAs) play important roles in carcinogenesis. However, the
effect of lncRNA on chemoresistance and RNA alternative splicing remains largely …

[HTML][HTML] Fusobacterium nucleatum promotes metastasis in colorectal cancer by activating autophagy signaling via the upregulation of CARD3 expression

Y Chen, Y Chen, J Zhang, P Cao, W Su, Y Deng… - Theranostics, 2020 - ncbi.nlm.nih.gov
Aims: We aimed to measure the abundance of Fusobacterium nucleatum (F. nucleatum) in
colorectal cancer (CRC) tissues from patients and to uncover the function of this bacterium in …

Liquid biopsy and tumor heterogeneity in metastatic solid tumors: the potentiality of blood samples

M Russano, A Napolitano, G Ribelli, M Iuliani… - Journal of Experimental …, 2020 - Springer
In a large number of cancer types, treatment selection depends on the presence of specific
tumor biomarkers. Due to the dynamic nature of cancer, very often these predictive …

piRBase: integrating piRNA annotation in all aspects

J Wang, Y Shi, H Zhou, P Zhang, T Song… - Nucleic acids …, 2022 - academic.oup.com
Piwi-interacting RNAs are a type of small noncoding RNA that have various functions.
piRBase is a manually curated resource focused on assisting piRNA functional analysis …