High-throughput studies of biological systems are rapidly accumulating a wealth of'omics'-
scale data. Visualization is a key aspect of both the analysis and understanding of these …

Lipids play an important role in physiology and pathophysiology of living systems. Until a
few decades ago, the number of lipid molecules that were chemically characterized was a …

Substantial progress has been made in the field of “omics” research (eg, Genomics,
Transcriptomics, Proteomics, and Metabolomics), leading to a vast amount of biological …

Background The increasing availability and diversity of omics data in the post-genomic era
offers new perspectives in most areas of biomedical research. Graph-based biological …

Networks are typically visualized with force-based or spectral layouts. These algorithms lack
reproducibility and perceptual uniformity because they do not use a node coordinate system …

Abstract Ocean Sampling Day was initiated by the EU-funded Micro B3 (Marine Microbial
Biodiversity, Bioinformatics, Biotechnology) project to obtain a snapshot of the marine …

Macroautophagy, a catabolic process of cellular self-digestion, is an important tumor cell
survival mechanism and a potential target in antineoplastic therapies. Recent discoveries …

Many tools exist for visually exploring biological networks including well-known examples
such as Cytoscape, VisANT, Pathway Studio and Patika. These systems play a key role in …

Abstract “Α picture is worth a thousand words.” This widely used adage sums up in a few
words the notion that a successful visual representation of a concept should enable easy …

Background Functional analyses of genomic data within the context of a priori biomolecular
networks can give valuable mechanistic insights. However, such analyses are not a trivial …