Liposomes are a unique platform for drug delivery, and a number of liposomal formulations
have already been commercialized. Doxil is a representative example, which uses …

Cancer is a leading cause of mortality and morbidity worldwide. Despite major
improvements in current therapeutic methods, ideal therapeutic strategies for improved …

Phosphatidylserine (PS) is an anionic phospholipid in the eukaryotic membrane and is
abundant in the brain. Accumulated studies have revealed that PS is involved in the multiple …

Cytotoxic lymphocytes are critical in our immune defence against cancer and infection.
Cytotoxic T lymphocytes and Natural Killer cells can directly lyse malignant or infected cells …

The fundamental differences in phospholipids between bacterial and mammalian cell
membranes present remarkable opportunities for antimicrobial design. However, it is …

The development of durable new antiviral therapies is challenging, as viruses can evolve
rapidly to establish resistance and attenuate therapeutic efficacy. New compounds that …

Simple Summary Colorectal cancer (CRC) is the third-most diagnosed cancer and the
second-leading cause of cancer-related deaths worldwide. Limitations in early and accurate …

Lysophosphatidylserine (lyso-PS) has emerged as yet another important signaling
lysophospholipid in mammals, and deregulation in its metabolism has been directly linked to …

Phosphatidylinositol-3-phosphate (PtdIns (3) P) is essential for cell survival, and its
intracellular synthesis is spatially and temporally regulated. It has major roles in two …

Native mass spectrometry (MS) with nanodiscs is a promising technique for characterizing
membrane protein and peptide interactions in lipid bilayers. However, prior studies have …