Leukaemia is a dangerous malignancy that causes thousands of deaths every year
throughout the world. The rate of morbidity and mortality is significant despite many …

Simple Summary The translocator protein (TSPO) has been under extensive investigation as
a specific marker in positron emission tomography (PET) to visualize brain lesions following …

Translocator protein 18 kDa (TSPO) was previously known as the peripheral
benzodiazepine receptor (PBR) in eukaryotes, where it is mainly localized to the …

Purpose Glioma patients, especially recurrent glioma, suffer from a poor prognosis. While
advances to classify glioma on a molecular level improved prognostication at initial …

TSPO is a receptor involved in the regulation of cellular proliferation, apoptosis and
mitochondrial functions. Previous studies showed that the expression of TSPO protein …

Translocator protein (TSPO), a 18 kDa protein found in the outer mitochondrial membrane,
has historically been associated with the transport of cholesterol in highly steroidogenic …

Recent loss-of-function studies in tissue-specific as well as global Tspo (Translocator
Protein 18 kDa) knockout mice have not confirmed its long assumed indispensability for the …

The mitochondrial translocator protein (TSPO) is a high affinity cholesterol binding protein
which is primarily located in the outer mitochondrial membrane where it has been shown to …

Mitochondria mediate critical cellular processes, including proliferation, apoptosis, and
immune responses; as such, their dysfunction is pathogenic in many neurodegenerative …

In the present review we summarize observations to date supporting the concept that
neuroactive steroids are synthesized in the peripheral nervous system, regulate the …