Several collagen subtypes have been identified in hyaline articular cartilage. The main and
most abundant collagens are type II, IX and XI collagens. The minor and less abundant …

Bone implants and devices are a rapidly growing field within biomedical research, and
implants have the potential to significantly improve human and animal health. Animal …

The aims of this study were to (1) determine whether platelet-rich plasma (PRP) could be
prepared as a bioactive scaffold capable of endogenous growth factor release for cartilage …

Much research is currently ongoing into new therapies for cartilage defect repair with new
biomaterials frequently appearing which purport to have significant regenerative capacity …

Articular cartilage is integral to the mechanical function of many joints in the body. When
injured, cartilage lacks the capacity to self-heal, and thus, therapies and replacements have …

MSCs are known as multipotent mesenchymal stem cells that have been found capable of
differentiating into various lineages including cartilage. However, recent studies suggest …

Articular cartilage defects represent an inciting factor for future osteoarthritis (OA) and
degenerative joint disease progression. Despite multiple clinically available therapies that …

In the knee joint, the purpose of the cartilage-bone interface is to maintain structural integrity
of the osteochondral unit during walking, kneeling, pivoting, and jumping–during which …

Cartilage repair in terms of replacement, or regeneration of damaged or diseased articular
cartilage with functional tissue, is the 'holy grail'of joint surgery. A wide spectrum of strategies …

Damaged cartilage has poor self-healing ability and usually progresses to scar or
fibrocartilaginous tissue, and finally degenerates to osteoarthritis (OA). Here we …