Myocardial ischaemia resulting from obstructive coronary artery disease is a major cause of
morbidity and mortality in the developed world. Coronary artery bypass graft (CABG) surgery …

Occlusive arterial disease is a leading cause of morbidity and mortality worldwide. Aside
from balloon angioplasty, bypass graft surgery is the most commonly performed …

Advances in standards of care have extended the life expectancy of patients with kidney
failure. However, options for chronic vascular access for haemodialysis—an essential part of …

Blood vessels are constantly exposed to mechanical stimuli such as shear stress due to flow
and pulsatile stretch. The extracellular matrix maintains the structural integrity of the vessel …

Inflammation plays a critical role in the response to and survival from injuries and/or
infections. It occurs in two phases: initiation and resolution; however, when these events do …

After the creation of an autogenous lower extremity bypass graft, the vein must undergo a
series of dynamic structural changes to stabilize the arterial hemodynamic forces. These …

Bypass surgery is one of the most frequently used strategies to revascularize tissues
downstream occlusive atherosclerotic lesions. For venous bypass surgery the great …

With the increasing prevalence of end-stage renal disease, there is a growing need for
hemodialysis. Arteriovenous fistulae (AVF) are the preferred type of vascular access for …

Unresolved inflammation is central to the pathophysiology of commonly occurring vascular
diseases such as atherosclerosis, aneurysm, and deep vein thrombosis—conditions that are …

Tissue-engineered vascular grafts (TEVGs) have enormous potential for vascular
replacement therapy. However, thrombosis and intimal hyperplasia are important problems …