Small molecule drug discovery has been propelled by the continual development of novel
scientific methodologies to occasion therapeutic advances. Although established …

The separation and detection of isomers remains a challenge for many areas of mass
spectrometry. This article highlights laser photodissociation and ion mobility strategies that …

Appending conformationally restraining ring systems to the cyanine chromophore creates
exceptionally bright fluorophores in the visible range. Here, we report the application of this …

The review is devoted to mechanically sensitive indoline spiropyrans and their structural
features. Recent advances in the study of their isomerization processes are considered …

Differential Ion Mobility Spectrometry (DIMS) provides orthogonal separation to mass
spectrometry, and DIMS combined with the high sensitivity of a quadrupole ion-trap is shown …

This manuscript describes a new experimental setup that allows to perform tandem ion
mobility spectrometry (IMS) measurements and which is coupled to a high resolution time-of …

Donor–acceptor Stenhouse adducts (DASAs) are a new class of photoswitching molecules
with excellent fatigue resistance and synthetic tunability. Here, tandem ion mobility mass …

We report the first results from a new instrument capable of acquiring infrared spectra of
mobility-selected ions. This demonstration involves using ion mobility to first separate the …

We report experimental and computational studies of protonated adenine C-8 σ-radicals that
are presumed yet elusive reactive intermediates of oxidative damage to nucleic acids. The …

Photodissociation action spectroscopy is often used as a proxy for measuring gas-phase
absorption spectra of ions in a mass spectrometer. Although the potential discrepancy …