Apoptotic mechanisms of quercetin in liver cancer: recent trends and advancements
Due to rising incidence rates of liver cancer and worries about the toxicity of current
chemotherapeutic medicines, the hunt for further alternative methods to treat this malignancy …
chemotherapeutic medicines, the hunt for further alternative methods to treat this malignancy …
Anticancer and apoptosis inducing potential of quercetin against a wide range of human malignancies
Quercetin, a flavonoid, is a dietary component that has attracted the attention of dietitians
and medicinal chemists due to its anticancer potential. It is an antioxidant that has a …
and medicinal chemists due to its anticancer potential. It is an antioxidant that has a …
Resveratrol modulates chemosensitisation to 5-FU via β1-integrin/HIF-1α Axis in CRC tumor microenvironment
Frequent development of resistance to chemotherapeutic agents such as 5-flourouracil (5-
FU) complicates the treatment of advanced colorectal cancer (CRC). Resveratrol is able to …
FU) complicates the treatment of advanced colorectal cancer (CRC). Resveratrol is able to …
Diarylheptanoids/sorafenib as a potential anticancer combination against hepatocellular carcinoma: the p53/MMP9 axis of action
Hepatocellular carcinoma (HCC) is a serious and potentially fatal form of cancer associated
with liver damage. New anticancer drugs are increasingly needed due to the increasing …
with liver damage. New anticancer drugs are increasingly needed due to the increasing …
Carvacrol enhances anti-tumor activity and mitigates cardiotoxicity of sorafenib in thioacetamide-induced hepatocellular carcinoma model through inhibiting TRPM7
Abstract Aims Sorafenib (Sora) represents one of the few effective drugs for the treatment of
advanced hepatocellular carcinoma (HCC), while resistance and cardiotoxicity limit its …
advanced hepatocellular carcinoma (HCC), while resistance and cardiotoxicity limit its …
Discovering the protective effects of quercetin on aflatoxin b1-induced toxicity in bovine foetal hepatocyte-derived cells (BFH12)
M Pauletto, M Giantin, R Tolosi, I Bassan, A Bardhi… - Toxins, 2023 - mdpi.com
Aflatoxin B1 (AFB1) induces lipid peroxidation and mortality in bovine foetal hepatocyte-
derived cells (BFH12), with underlying transcriptional perturbations associated mainly with …
derived cells (BFH12), with underlying transcriptional perturbations associated mainly with …
Protective role of hesperetin in sorafenib-induced hepato-and neurotoxicity in mice via modulating apoptotic pathways and mitochondrial reprogramming
D Zaafar, HMA Khalil, R Elnaggar, DZ Saad… - Life Sciences, 2024 - Elsevier
Introduction Sorafenib, an FDA-approved standard chemotherapy for advanced
hepatocellular carcinoma, is associated with numerous adverse effects that significantly …
hepatocellular carcinoma, is associated with numerous adverse effects that significantly …
Quercetin prevents the ferroptosis of OPCs by inhibiting the Id2/transferrin pathway
Y Wang, W Li, M Wang, H Chen, Y Li, W Wei… - Chemico-Biological …, 2023 - Elsevier
Spinal cord injury (SCI) is a destructive neurological disorder that causes impaired mobility,
sensory, and autonomic dysfunctions. The loss of oligodendrocyte progenitor cells (OPCs) …
sensory, and autonomic dysfunctions. The loss of oligodendrocyte progenitor cells (OPCs) …
Dual-drug controllable co-assembly nanosystem for targeted and synergistic treatment of hepatocellular carcinoma
JQ Le, XH Song, LW Tong, YQ Lin, KK Feng… - Journal of Colloid and …, 2024 - Elsevier
The effectiveness of chemotherapeutic agents for hepatocellular carcinoma (HCC) is
unsatisfactory because of tumor heterogeneity, multidrug resistance, and poor target …
unsatisfactory because of tumor heterogeneity, multidrug resistance, and poor target …
Baicalein ameliorates polymyxin B-induced acute renal injury by inhibiting ferroptosis via regulation of SIRT1/p53 acetylation
M Yu, H Li, B Wang, Z Wu, S Wu, G Jiang… - Chemico-Biological …, 2023 - Elsevier
The polypeptide antibiotic Polymyxin B (PMB) can cause acute kidney injury (AKI), we found
that ferroptosis is one of the main mechanisms of renal injury caused by PMB. It was …
that ferroptosis is one of the main mechanisms of renal injury caused by PMB. It was …