Among mouse mammary tumor models, syngeneic cell lines present an advantage for the
study of immune response. However, few of these models are well characterized. The tumor …

Chemotherapy is an important tool for the management of solid tumors including breast
cancers (BC). Its neo-adjuvant and adjuvant use is important for shrinking tumor size and …

Cancer cell radioresistance is the primary cause of the decreased curability of non–small
cell lung cancer (NSCLC) observed in patients receiving definitive radiotherapy (RT) …

Cardiac fibroblasts (CFs) undergo senescence in reaction to different stressors, leading to a
poor prognosis of cardiac disease. Doxorubicin (Doxo) is an antineoplastic drug with strong …

During ageing molecular damage leads to the accumulation of several hallmarks of ageing
including mitochondrial dysfunction, cellular senescence, genetic instability and chronic …

Cancer continues to place a heavy burden on healthcare systems around the world.
Although cancer survivorship continues to improve, cardiotoxicity leading to cardiomyopathy …

Several fractions of Calotropis gigantea extracts have been proposed to have potential
anticancer activity in many cancer models. The present study evaluated the anticancer …

Signals from the tumor microenvironment (TME) have a profound influence on the
maintenance and progression of cancers. Chronic inflammation and the infiltration of …

Simple Summary The incidence of breast cancer has increased rapidly in recent years.
Aging is one of the risk factors for advanced breast cancer. More and more studies have …

El envejecimiento se caracteriza por deterioro de las funciones del organismo y se ha
relacionado con un mayor riesgo de desarrollar enfermedades cardiovasculares (ECV) …