Plasmodium vivax is an important cause of malaria, associated with a significant public
health burden. Whilst enhanced malaria-control activities have successfully reduced the …

Plasmodium vivax is the most geographically widespread human malaria parasite. Global
malaria efforts have been less successful at reducing the burden of P. vivax compared to P …

Background Plasmodium vivax exacts a significant toll on health worldwide, yet few efforts to
date have quantified the extent and temporal trends of its global distribution. Given the …

Background Primaquine is used to eliminate Plasmodium vivax hypnozoites, but its optimal
dosing regimen remains unclear. We undertook a systematic review and individual patient …

Emerging antimalarial drug resistance may undermine current efforts to control and
eliminate Plasmodium vivax, the most geographically widespread yet neglected human …

Background Despite recent intensification of control measures, Plasmodium vivax poses a
major challenge for malaria elimination efforts. Liver-stage hypnozoite parasites that cause …

Plasmodium vivax malaria continues to cause a significant burden of disease in the Asia-
Pacific, the Horn of Africa, and the Americas. In addition to schizontocidal treatment, the 8 …

Background As malaria endemic countries strive towards elimination, intensified spatial
heterogeneities of local transmission could undermine the effectiveness of traditional …

Background Malaria control activities can have a disproportionately greater impact on
Plasmodium falciparum than on P. vivax in areas where both species are coendemic. We …

Abstract Background Eliminating Plasmodium vivax will require targeting the hidden liver-
stage reservoir of hypnozoites. This necessitates new interventions balancing the benefit of …