The immunological hallmarks of sepsis include the inflammation-mediated cytokine storm,
apoptosis-driven lymphopenia, and prolonged immunoparalysis. Although early clinical …

Sepsis is a life threatening disease that is caused by a dysregulated host immune response
to infection, resulting in tissue damage and organ dysfunction, which account for a high in …

The global health burden due to sepsis and the associated cytokine storm is substantial.
While early intervention has improved survival during the cytokine storm, those that survive …

Sepsis, an amplified immune response to systemic infection, is characterized by a transient
cytokine storm followed by chronic immune dysfunction. Consequently, sepsis survivors are …

The dysregulated sepsis-induced cytokine storm evoked during systemic infection consists
of biphasic and interconnected pro-and anti-inflammatory responses. The contrasting …

The dysregulated host response and organ damage following systemic infection that
characterizes a septic event predisposes individuals to a chronic immunoparalysis state …

Bloodstream infection (BSI) refers to the infection of blood by pathogens. Severe immune
response to BSI can lead to sepsis, a systemic infection leading to multiple organ …

Purpose Studies on overall immune infiltration and pyroptosis in patients with multiple
sclerosis (MS) are limited. This study explored immune cell infiltration and pyroptosis in MS …

The self‐non‐self model and the danger model are designed to understand how an immune
response is induced. These models are not meant to predict if an immune response may …

Prolonged critical care stays commonly follow trauma, severe burn injury, sepsis, ARDS, and
complications of major surgery. Although patients leave critical care following homeostatic …