Prognostic and predictive biomarkers for immunotherapy in advanced renal cell carcinoma

M Rosellini, A Marchetti, V Mollica, A Rizzo… - Nature Reviews …, 2023 - nature.com
The therapeutic algorithm of renal cell carcinoma has been revolutionized by the approval of
immunotherapy agents by regulatory agencies. However, objective and durable responses …

Circulating tumor DNA in biliary tract cancer: current evidence and future perspectives

A Rizzo, AD Ricci, S Tavolari… - Cancer genomics & …, 2020 - cgp.iiarjournals.org
Peripheral blood of cancer patients “physiologically” presents cells and cellular components
deriving from primary or metastatic sites, including circulating tumor cells (CTCs), circulating …

Tumor copy number alteration burden is a pan-cancer prognostic factor associated with recurrence and death

H Hieronymus, R Murali, A Tin, K Yadav, W Abida… - Elife, 2018 - elifesciences.org
The level of copy number alteration (CNA), termed CNA burden, in the tumor genome is
associated with recurrence of primary prostate cancer. Whether CNA burden is associated …

Comprehensive characterization of cell-free tumor DNA in plasma and urine of patients with renal tumors

CG Smith, T Moser, F Mouliere, J Field-Rayner… - Genome medicine, 2020 - Springer
Background Cell-free tumor-derived DNA (ctDNA) allows non-invasive monitoring of
cancers, but its utility in renal cell cancer (RCC) has not been established. Methods Here, a …

Translational application of circulating DNA in oncology: review of the last decades achievements

NO Tuaeva, L Falzone, YB Porozov, AE Nosyrev… - Cells, 2019 - mdpi.com
In recent years, the introduction of new molecular techniques in experimental and clinical
settings has allowed researchers and clinicians to propose circulating-tumor DNA (ctDNA) …

Theranostic Lipid Nanoparticles for Renal Cell Carcinoma

X Mao, G Wang, Z Wang, C Duan, X Wu… - Advanced …, 2023 - Wiley Online Library
Renal cell carcinoma (RCC) is a common urological malignancy and represents a leading
threat to healthcare. Recent years have seen a series of progresses in the early diagnosis …

Prognostication in kidney cancer: recent advances and future directions

J Graham, S Dudani, DYC Heng - Journal of Clinical Oncology, 2018 - ascopubs.org
The most common type of cancer originating in the kidney is renal cell carcinoma (RCC). In
both localized and advanced RCC, a number of clinical, pathologic, and molecular factors …

Biomarkers for renal cell carcinoma recurrence: state of the art

M Marchioni, JG Rivas, A Autran, M Socarras… - Current Urology …, 2021 - Springer
Abstract Purpose of Review We aim to summarize the current state of art about the possible
use of biomarkers for predicting renal cell carcinoma (RCC) recurrence after curative …

Early detection of kidney cancer using urinary proteins: a truly non‐invasive strategy

JG Flitcroft, J Verheyen, T Vemulkar… - BJU …, 2022 - Wiley Online Library
Objectives To review urinary protein biomarkers as potential non‐invasive, easily
obtainable, early diagnostic tools in renal cell carcinoma (RCC). Methods A PubMed …

The current status of the clinical utility of liquid biopsies in cancer

A Snow, D Chen, JE Lang - Expert review of molecular diagnostics, 2019 - Taylor & Francis
Introduction: Liquid biopsies have attracted considerable attention as potential diagnostic,
prognostic, predictive, and screening assays in oncology. The term liquid biopsies include …