Thrombosis in cerebral aneurysms and the computational modeling thereof: a review

MN Ngoepe, AF Frangi, JV Byrne, Y Ventikos - Frontiers in physiology, 2018 - frontiersin.org
Thrombosis is a condition closely related to cerebral aneurysms and controlled thrombosis
is the main purpose of endovascular embolization treatment. The mechanisms governing …

Comparison of intracranial aneurysm flow quantification techniques: standard PIV vs stereoscopic PIV vs tomographic PIV vs phase-contrast MRI vs CFD

C Roloff, D Stucht, O Beuing, P Berg - Journal of neurointerventional …, 2019 - jnis.bmj.com
Image-based hemodynamic simulations to assess the rupture risk or improve the treatment
planning of intracranial aneurysms have become popular recently. However, due to strong …

Study and modeling of the thrombosis of small cerebral aneurysms, with and without flow diverter, by the lattice Boltzmann method

F Mezali, K Naima, S Benmamar, A Liazid - Computer Methods and …, 2023 - Elsevier
Background and objective Small cerebral aneurysms are currently commonly treated non-
invasively by flow diverter device. These stents lead to thrombotic occlusion of the aneurysm …

[HTML][HTML] Influence of vortical structures on fibrin clot formation in cerebral aneurysms: A two-dimensional computational study

T Ngwenya, D Grundlingh, MN Ngoepe - Journal of Biomechanics, 2024 - Elsevier
Thrombosis is an important contributor to cerebral aneurysm growth and progression. A
number of sophisticated multiscale and multiphase in silico models have been developed …

Multiphase continuum modeling of thrombosis in aneurysms and recirculation zones

A Bouchnita, AV Belyaev, V Volpert - Physics of Fluids, 2021 - pubs.aip.org
Aneurysms of saccular shape are usually associated with a slow, almost stagnant blood
flow, as well as a consequent emergence of blood clots. Despite the practical importance …

Reconstructing patient-specific cerebral aneurysm vasculature for in vitro investigations and treatment efficacy assessments

VK Chivukula, MR Levitt, A Clark, MC Barbour… - Journal of Clinical …, 2019 - Elsevier
Perianeurysmal hemodynamics play a vital role in the initiation, growth and rupture of
intracranial aneurysms. In vitro investigations of aneurysmal hemodynamics are helpful to …

Evaluation of a desktop 3D printed rigid refractive-indexed-matched flow phantom for PIV measurements on cerebral aneurysms

WH Ho, IJ Tshimanga, MN Ngoepe, MC Jermy… - Cardiovascular …, 2020 - Springer
Purpose Fabrication of a suitable flow model or phantom is critical to the study of biomedical
fluid dynamics using optical flow visualization and measurement methods. The main …

[HTML][HTML] A computational model for prediction of clot platelet content in flow-diverted intracranial aneurysms

A Sarrami-Foroushani, T Lassila, SM Hejazi… - Journal of …, 2019 - Elsevier
Abstract Treatment of intracranial aneurysms with flow-diverting stents is a safe and
minimally invasive technique. The goal is stable embolisation that facilitates stent …

In vitro evaluation of flow diverter performance using a human fibrinogen–based flow model

C Bilgin, EA Bayraktar, AA Oliver, J Li, JR Cebral… - Journal of …, 2024 - thejns.org
OBJECTIVE Fibrin deposition represents a key step in aneurysm occlusion, promoting
endothelization of implants and connective tissue organization as part of the aneurysm …

Fabrication, characterization and numerical validation of a novel thin-wall hydrogel vessel model for cardiovascular research based on a patient-specific stenotic …

A Shiravand, K Richter, P Willmann, P Eulzer… - Scientific Reports, 2024 - nature.com
In vitro vascular models, primarily made of silicone, have been utilized for decades for
studying hemodynamics and supporting the development of implants for catheter-based …