Approaches to integrating metabolomics and multi-omics data: a primer

T Jendoubi - Metabolites, 2021 - mdpi.com
Metabolomics deals with multiple and complex chemical reactions within living organisms
and how these are influenced by external or internal perturbations. It lies at the heart of …

Focus on the glycerophosphocholine pathway in choline phospholipid metabolism of cancer

K Sonkar, V Ayyappan, CM Tressler… - NMR in …, 2019 - Wiley Online Library
Activated choline metabolism is a hallmark of carcinogenesis and tumor progression, which
leads to elevated levels of phosphocholine and glycerophosphocholine in all types of …

From Nontargeted to Targeted Analysis: Feature Selection in the Differentiation of Truffle Species (Tuber spp.) Using 1H NMR Spectroscopy and Support Vector …

T Mix, J Janneschütz, R Ludwig… - Journal of Agricultural …, 2023 - ACS Publications
The price of different truffle types varies according to their culinary value, sometimes by more
than a factor of 10. Nonprofessionals can hardly distinguish visually the species within the …

Metabolomics and EMT markers of breast cancer: a crosstalk and future perspective

AK Pal, P Sharma, A Zia, D Siwan, D Nandave… - Pathophysiology, 2022 - mdpi.com
Cancer cells undergo transient EMT and MET phenomena or vice versa, along with the
parallel interplay of various markers, often correlated as the determining factor in decoding …

Mechanisms governing metabolic heterogeneity in breast cancer and other tumors

S Patra, N Elahi, A Armorer, S Arunachalam… - Frontiers in …, 2021 - frontiersin.org
Reprogramming of metabolic priorities promotes tumor progression. Our understanding of
the Warburg effect, based on studies of cultured cancer cells, has evolved to a more …

Non-conventional and investigational PET radiotracers for breast cancer: a systematic review

M Balma, V Liberini, M Racca, R Laudicella… - Frontiers in …, 2022 - frontiersin.org
Breast cancer is one of the most common malignancies in women, with high morbidity and
mortality rates. In breast cancer, the use of novel radiopharmaceuticals in nuclear medicine …

Dandelion extract inhibits triple-negative breast cancer cell proliferation by interfering with glycerophospholipids and unsaturated fatty acids metabolism

S Wang, H Hao, Y Jiao, J Fu, Z Guo, Y Guo… - Frontiers in …, 2022 - frontiersin.org
Triple-negative breast cancer (TNBC) is the most aggressive breast cancer subtype with
limited treatment options and a poor prognosis. TNBC exists widely reprogrammed lipid …

Molecular and metabolic alterations of 2,3-dihydroquinazolin-4(1H)-one derivatives in prostate cancer cell lines

LA Dahabiyeh, W Hourani, W Darwish, F Hudaib… - Scientific Reports, 2022 - nature.com
Prostate cancer (PC) is the second most common tumor in males worldwide. The lack of
effective medication and the development of multidrug resistance towards current …

Metabolomics: a promising diagnostic and therapeutic implement for breast cancer

Z Chen, Z Li, H Li, Y Jiang - OncoTargets and therapy, 2019 - Taylor & Francis
Breast cancer (BC) is the most commonly diagnosed cancer among women and the leading
cause of cancer death. Despite the advent of numerous diagnosis and treatment methods in …

Comparison of unsupervised machine-learning methods to identify metabolomic signatures in patients with localized breast cancer

J Gal, C Bailleux, D Chardin, T Pourcher… - Computational and …, 2020 - Elsevier
Genomics and transcriptomics have led to the widely-used molecular classification of breast
cancer (BC). However, heterogeneous biological behaviors persist within breast cancer …