The basic unit of kidney function is the nephron. In the mouse, around 14,000 nephrons form
in a 10-day period extending into early neonatal life, while the human fetus forms the adult …

Congenital abnormalities of the kidney and urinary tract (CAKUT) are one of the leading
congenital defects to be identified on prenatal ultrasound. CAKUT represent a broad …

Background During normal human kidney development, nephrogenesis (the formation of
nephrons) is complete by term birth, with the majority of nephrons formed late in gestation …

Low nephron number—resulting, for example, from prematurity or developmental anomalies—
is a risk factor for the development of hypertension, chronic kidney disease and kidney …

Podocyte and glomerular research is center stage for the development of improved
preventive and therapeutic strategies for chronic progressive kidney diseases. Held April 3 …

The mammalian kidney develops from a simple epithelial bud to an arborized network of
tubules, which are fated to form the ureter, renal pelvis and collecting ducts. This process of …

During fetal development, nephrons of the metanephric kidney form from a mesenchymal
progenitor population that differentiates en masse before or shortly after birth. We explored …

As a result of preterm birth, immature kidneys are exposed to interventions in the NICU that
promote survival, but are nephrotoxic. Furthermore, the duration of renal development may …

In the kidney, formation of the functional filtration units, the nephrons, is essential for
postnatal life. During development, mesenchymal progenitors tightly regulate the balance …

Over a decade ago, it was proposed that the regulation of tubular repair in the kidney might
involve the recapitulation of developmental pathways. Although the kidney cannot generate …