Imidazoquinoline derivatives (IMDs) and related compounds function as synthetic agonists
of Toll-like receptors 7 and 8 (TLR7/8) and one is FDA approved for topical antiviral and skin …

Liposome as a revolutionizing carrier, has exhibited favorable aspects in drug delivery.
However, there are numerous challenges affecting its effectiveness. Hypersensitivity …

Vaccinology is one of the most important cornerstones in modern medicine, providing better
quality of life. The human immune system is composed of innate and adaptive immune …

Stimulation of monocytes with immunomodulating agents can harness the immune system to
treat a long range of diseases, including cancers, infections and autoimmune diseases. To …

Nanomedicine holds immense potential for therapeutic manipulation of phagocytic immune
cells. However, in vitro studies often fail to accurately translate to the complex in vivo …

Tumor immune escape is today recognized as an important cancer hallmark and is therefore
a major focus area in cancer therapy. Monocytes and dendritic cells (DCs), which are central …

Cationic liposomes specifically target monocytes in blood, rendering them promising drug-
delivery tools for cancer immunotherapy, vaccines, and therapies for monocytic leukaemia …

With the continuous discovery of receptors that are closely involved in tumor occurrence and
progression, modulating the activity of these receptors to achieve tumor therapy via their …

Abstract Development of simple and fully characterized immunomodulatory molecules is an
active area of research to enhance current immunotherapies. Monophosphoryl lipid A …

Liposomes are versatile delivery systems and immunological adjuvants that not only can
load various antigens, such as proteins, peptides, nucleic acids and carbohydrates, but also …