Precision medicine and the future of cardiovascular diseases: a clinically oriented comprehensive review

Y Sethi, N Patel, N Kaka, O Kaiwan, J Kar… - Journal of clinical …, 2023 - mdpi.com
Cardiac diseases form the lion's share of the global disease burden, owing to the paradigm
shift to non-infectious diseases from infectious ones. The prevalence of CVDs has nearly …

Multiomics technologies: role in disease biomarker discoveries and therapeutics

MA Dar, A Arafah, KA Bhat, A Khan… - Briefings in …, 2023 - academic.oup.com
Medical research has been revolutionized after the publication of the full human genome.
This was the major landmark that paved the way for understanding the biological functions …

Multi-omics integration to identify the genetic expression and protein signature of dilated and ischemic cardiomyopathy

K Portokallidou, N Dovrolis, G Ragia… - Frontiers in …, 2023 - frontiersin.org
Introduction Heart failure (HF) is a complex clinical syndrome leading to high morbidity. In
this study, we aimed to identify the gene expression and protein signature of HF main …

How Can Proteomics Help to Elucidate the Pathophysiological Crosstalk in Muscular Dystrophy and Associated Multi-System Dysfunction?

P Dowling, C Trollet, E Negroni, D Swandulla… - Proteomes, 2024 - mdpi.com
This perspective article is concerned with the question of how proteomics, which is a core
technique of systems biology that is deeply embedded in the multi-omics field of modern …

Bioinformatic Analysis of the Subproteomic Profile of Cardiomyopathic Tissue

S Murphy, M Zweyer, D Swandulla… - … : Methods and Protocols, 2022 - Springer
Following large-scale protein separation by two-dimensional gel electrophoresis or liquid
chromatography, mass spectrometry–based proteomics can be used for the swift …

Contribution of laboratory medicine and emerging technologies to cardiovascular risk reduction via exposome analysis: an opinion of the IFCC Division on Emerging …

D Gruson, E Fux, T Kemaloğlu Öz, B Gouget… - Clinical Chemistry and …, 2024 - degruyter.com
This opinion article highlights the critical role of laboratory medicine and emerging
technologies in cardiovascular risk reduction through exposome analysis. The exposome …

Genomics and the “-Omics”

F Saluzzo, A Spitaleri, DM Cirillo - Global Health Essentials, 2023 - Springer
The progresses in the “omics” field have revolutionized the approach to diagnosis and
treatment for several communicable and non-communicable diseases. The application of …