Brain-derived neurotrophic factor (BDNF) belongs to a family of small secreted proteins that
also include nerve growth factor, neurotrophin 3, and neurotrophin 4. BDNF stands out …

The mechanisms involved in plasticity in the nervous system are thought to support
cognition, and some of these processes are affected during normal ageing. Notably …

Fear conditioning is a valuable behavioral paradigm for studying the neural basis of
emotional learning and memory. The lateral nucleus of the amygdala (LA) is a crucial site of …

This study was designed to identify molecular mechanisms by which exercise affects
synaptic-plasticity in the hippocampus, a brain area whose function, learning and memory …

Exercise, a behavior that is inherently associated with energy metabolism, impacts the
molecular systems important for synaptic plasticity and learning and memory. This implies …

The NMDA subtype of glutamate receptors (NMDAR) at excitatory neuronal synapses plays
a key role in synaptic plasticity. The extracellular signal-regulated kinase (ERK1, 2 or ERK) …

The glutamate system is involved in many aspects of neuronal synaptic strength and
function during development and throughout life. Synapse formation in early brain …

Transcranial direct current stimulation (tDCS) can produce a lasting polarity-specific
modulation of cortical excitability in the brain, and it is increasingly used in experimental and …

In this article, we have characterized and compared gene expression profiles from laser
capture microdissected neurons in six functionally and anatomically distinct regions from …

Epilepsy is one of the most common neurological disorders. Although epilepsy can be
idiopathic, it is estimated that up to 50% of all epilepsy cases are initiated by neurological …