Respiratory infections cause tremendous morbidity and mortality worldwide. Amongst these
diseases, tuberculosis (TB), a bacterial illness caused by Mycobacterium tuberculosis which …

The continued pressure of COVID-19 on public health worldwide underlines the need for a
better understanding of the mechanisms of disease caused by severe acute respiratory …

Immunocompromised people are at high risk of prolonged severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) infection and progression to severe coronavirus …

The transmission bottleneck, defined as the number of viruses shed from one host to infect
another, is an important determinant of the rate of virus evolution and the level of immunity …

Small animal models have been a challenge for the study of SARS-CoV-2 transmission, with
most investigators using golden hamsters or ferrets. Mice have the advantages of low cost …

Vaccination has proven effective against SARS‐CoV‐2 infection but vaccines were
originally based on the wild type and emerging variants have led to a decrease in protective …

Despite significant effort, a clear understanding of host tissue-specific responses and their
implications for immunopathogenicity against the severe acute respiratory syndrome …

As SARS-CoV-2 continues to evolve antigenically to escape vaccine-or infection-induced
immunity, suitable animal models are needed to study novel interventions against viral …

Respiratory infectious diseases are more likely to occur in indoor environments. Therefore,
the probability of transmission when sharing the same indoor space with an infected …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a highly transmissible
respiratory pathogen whose main transmission route is respiratory droplets and/or aerosols …