[HTML][HTML] Viruses Identified in Shrews (Soricidae) and Their Biomedical Significance

HY Gong, RX Chen, SM Tan, X Wang, JM Chen… - Viruses, 2024 - mdpi.com
Shrews (Soricidae) are common small wild mammals. Some species of shrews, such as
Asian house shrews (Suncus murinus), have a significant overlap in their habitats with …

[HTML][HTML] Alveolar Macrophages in Viral Respiratory Infections: Sentinels and Saboteurs of Lung Defense

P Pöpperl, M Stoff, A Beineke - International Journal of Molecular …, 2025 - mdpi.com
Respiratory viral infections continue to cause pandemic and epidemic outbreaks in humans
and animals. Under steady-state conditions, alveolar macrophages (AlvMϕ) fulfill a …

Epidemiological investigation and genetic evolutionary analysis of PRRSV-1 on a pig farm in China

C Li, H Xu, J Zhao, B Gong, Q Sun, L Xiang… - Frontiers in …, 2022 - frontiersin.org
Porcine reproductive and respiratory syndrome virus (PRRSV) has brought serious
economic losses to pig industry. PRRSV-1 have existed in China for more than 25 years …

The full-length nsp2 replicase contributes to viral assembly in highly pathogenic PRRSV-2

YZ Bai, S Wang, Y Sun, YG Liu, HL Zhang… - Journal of …, 2024 - journals.asm.org
Porcine reproductive and respiratory syndrome viruses (PRRSVs) are significant pathogens
that affect the global swine industry. Its virions consist of a central core composed of …

Analysis of recombinant characteristics based on 949 PRRSV-2 genomic sequences obtained from 1991 to 2021 shows that viral multiplication ability contributes to …

X Cui, D Xia, X Huang, Y Sun, M Shi… - Microbiology …, 2022 - Am Soc Microbiol
Porcine reproductive and respiratory syndrome (PRRS) is one of the most economically
important diseases affecting the pig-raising industry. The PRRS virus (PRRSV) has high …

Genomic Characterization and Pathogenicity of BJEU06‐1‐Like PRRSV‐1 ZD‐1 Isolated in China

H Xu, B Gong, Q Sun, C Li, J Zhao… - Transboundary and …, 2023 - Wiley Online Library
Porcine reproductive and respiratory syndrome virus (PRRSV)‐1 and PRRSV‐2 have long
been cocirculating in China. To date, all PRRSV‐1 strains in China have been classified as …

Astragaloside IV regulates cGAS-STING signaling pathway to alleviate immunosuppression caused by PRRSV infection

K Song, JY Yu, J Li, M Li, LY Peng, PF Yi - Viruses, 2023 - mdpi.com
Porcine reproductive and respiratory syndrome virus (PRRSV) poses a global threat to pig
health and results in significant economic losses. Impaired innate and adaptive immune …

[HTML][HTML] Genetically modified pigs lacking CD163 PSTII-domain-coding exon 13 are completely resistant to PRRSV infection

B Salgado, RB Rivas, D Pinto, TS Sonstegard… - Antiviral Research, 2024 - Elsevier
CD163 expressed on cell surface of porcine alveolar macrophages (PAMs) serves as a
cellular entry receptor for porcine reproductive and respiratory syndrome virus (PRRSV) …

Porcine reproductive and respiratory syndrome virus infection upregulates negative immune regulators and T-cell exhaustion markers

J Chaudhari, CS Liew, JJM Riethoven… - Journal of …, 2021 - Am Soc Microbiol
Porcine alveolar macrophage (PAM) is one of the primary cellular targets for porcine
reproductive and respiratory syndrome virus (PRRSV), but less than 2% of PAMs are …

Infection dynamics, transmission, and evolution after an outbreak of porcine reproductive and respiratory syndrome virus

H Clilverd, G Martín-Valls, Y Li, M Martín… - Frontiers in …, 2023 - frontiersin.org
The present study was aimed at describing the infection dynamics, transmission, and
evolution of porcine reproductive and respiratory syndrome virus (PRRSV) after an outbreak …