A semi‐monolithic detector providing intrinsic DOI‐encoding and sub‐200 ps CRT TOF‐capabilities for clinical PET applications

F Mueller, S Naunheim, Y Kuhl, D Schug… - Medical …, 2022 - Wiley Online Library
Background Current clinical positron emission tomography (PET) systems utilize detectors
where the scintillator typically contains single elements of 3–6‐mm width and about 20‐mm …

Position estimation using neural networks in semi-monolithic PET detectors

M Freire, J Barrio, N Cucarella… - Physics in Medicine …, 2022 - iopscience.iop.org
Objective. The goal of this work is to experimentally compare the 3D spatial and energy
resolution of a semi-monolithic detector suitable for total-body positron emission tomography …

Analysis of a convex time skew calibration for light sharing-based PET detectors

S Naunheim, Y Kuhl, T Solf, D Schug… - Physics in Medicine …, 2023 - iopscience.iop.org
Objective. Positron emission tomography (PET) detectors providing attractive coincidence
time resolutions (CTRs) offer time-of-flight information, resulting in an improved signal-to …

Improving the timing resolution of positron emission tomography detectors using boosted learning—a residual physics approach

S Naunheim, Y Kuhl, D Schug… - IEEE Transactions on …, 2023 - ieeexplore.ieee.org
Artificial intelligence (AI) is entering medical imaging, mainly enhancing image
reconstruction. Nevertheless, improvements throughout the entire processing, from signal …

High-throughput FPGA-based inference of gradient tree boosting models for position estimation in PET detectors

K Krueger, F Mueller, P Gebhardt… - … on Radiation and …, 2023 - ieeexplore.ieee.org
In modern large-scale positron emission tomography (PET) systems, transferring the
digitized raw detector data at high count rates to a centralized processing unit is a challenge …

Angular irradiation methods for DOI calibration of light-sharing detectors—a perspective for PET in-system calibration

Y Kuhl, S Naunheim, D Schug… - IEEE Transactions on …, 2023 - ieeexplore.ieee.org
Typical positron emission tomography (PET) detectors consist of one-layer segmented
scintillators coupled to silicon photomultipliers (SiPMs). Light-sharing detectors, eg, semi …

Near-field coded-mask technique and its potential for proton therapy monitoring

R Hetzel, V Urbanevych, A Bolke… - Physics in Medicine …, 2023 - iopscience.iop.org
Objective. Prompt-gamma imaging encompasses several approaches to the online
monitoring of the beam range or deposited dose distribution in proton therapy. We test one …

High throughput software-based gradient tree boosting positioning for PET systems

C Wassermann, F Mueller, T Dey… - Biomedical Physics …, 2021 - iopscience.iop.org
The supervised machine learning technique Gradient Tree Boosting (GTB) has shown good
accuracy for position estimation of gamma interaction in PET crystals for bench-top …

Evaluation of semi-monolithic scintillators with integrated RF shielding material for a higher integration of PET/MRI systems

EL Yin-Grossmann, F Mueller, Y Kuhl… - arXiv preprint arXiv …, 2022 - arxiv.org
The integration of PET into MRI to form a hybrid system requires often compromises for both
subsystems. For example, the integration might come at the cost of a reduced PET detector …

[PDF][PDF] Development of calibration methods and algorithms enabling (Semi-) monolithic detectors in clinical positron emission tomography

F Müller, VA Schulz, A Stahl, S Vandenberghe - 2023 - publications.rwth-aachen.de
Positron emission tomography (PET) is a functional medical imaging technique visualizing
metabolic processes with high sensitivity and application in research as well as in the clinic …