Reactive oxygen species and cell signaling. Review

D Averill-Bates - Biochimica et Biophysica Acta (BBA)-Molecular Cell …, 2024 - Elsevier
Reactive oxygen species (ROS) is a term encompassing a group of highly reactive oxygen-
derived molecules. In physiological systems, ROS production exists in concert with …

Premature ovarian insufficiency: a review on the role of oxidative stress and the application of antioxidants

YQ Shi, XT Zhu, SN Zhang, YF Ma, YH Han… - Frontiers in …, 2023 - frontiersin.org
Normal levels of reactive oxygen species (ROS) play an important role in regulating follicular
growth, angiogenesis and sex hormone synthesis in ovarian tissue. When the balance …

The antioxidant glutathione

DA Averill-Bates - Vitamins and hormones, 2023 - Elsevier
Reduced glutathione (GSH) is an essential non-enzymatic antioxidant in mammalian cells.
GSH can act directly as an antioxidant to protect cells against free radicals and pro-oxidants …

[HTML][HTML] Gill oxidative damage caused by acute ammonia stress was reduced through the HIF-1α/NF-κb signaling pathway in golden pompano (Trachinotus ovatus)

MJ Liu, HY Guo, B Liu, KC Zhu, L Guo, BS Liu… - Ecotoxicology and …, 2021 - Elsevier
This study aimed to investigate the intoxication mechanism of golden pompano (Trachinotus
ovatus) exposed to high ammonia levels and the effects on the immune and antioxidant …

Regulatory components of oxidative stress and inflammation and their complex interplay in carcinogenesis

LCP Dharshini, RR Rasmi, C Kathirvelan… - Applied Biochemistry …, 2023 - Springer
Cancer progression is closely linked to oxidative stress (OS) inflammation. OS is caused by
an imbalance between the amount of reactive oxygen species produced and antioxidants …

Selenium deficiency induces spleen pathological changes in pigs by decreasing selenoprotein expression, evoking oxidative stress, and activating inflammation and …

S Li, W Sun, K Zhang, J Zhu, X Jia, X Guo… - Journal of Animal …, 2021 - Springer
Background The immune system is one aspect of health that is affected by dietary selenium
(Se) levels and selenoprotein expression. Spleen is an important immune organ of the body …

Cross-talk between PPARγ, NF-κB, and p38 MAPK signaling mediates the ameliorating effects of bergenin against the iron overload-induced hepatotoxicity

SA Salama, MM Elshafey - Chemico-Biological Interactions, 2022 - Elsevier
Hepatotoxicity is a serious health problem that associates the iron overload diseases such
as thalassemia and sickle cell anemia. Induction of oxidative tissue injury and inflammation …

Glimepiride ameliorates renal toxicity induced by cadmium in mice: Modulation of Jun N terminal kinase (JNK)/nuclear factor kappa B (NF-κB) and phosphatidylinositol …

MK ElMahdy, MO Zaki, AA Al-Karmalawy, W Abdo… - Life Sciences, 2022 - Elsevier
Aims Nephrotoxicity is one of the most serious health consequences of cadmium (Cd) toxic
exposure. Cd was associated with nephrotoxicity through different mechanisms including …

Immunomodulatory effect of glabridin in ovalbumin induced allergic asthma and its comparison with methylprednisolone in a preclinical rodent model

H Muhammad, Z Salahuddin, T Akhtar… - Journal of Cellular …, 2023 - Wiley Online Library
Glabridin, a polyphenolic flavonoid derived from Glycyrrhiza glabra (licorice) roots, has
shown anti‐inflammatory and antioxidant properties. The current study sought to investigate …

Recent advances in nanocarriers-based drug delivery for cancer therapeutics: A review

P Yadav, J Jain, AP Sherje - Reactive and Functional Polymers, 2021 - Elsevier
Cancer prevalence is increasing in the last few decades with high mortality rates. It is a
leading cause of death globally. Due to the rising prevalence of cancer and the emergence …