The impact of the human thalamus on brain-wide information processing

JM Shine, LD Lewis, DD Garrett… - Nature Reviews …, 2023 - nature.com
The thalamus is a small, bilateral structure in the diencephalon that integrates signals from
many areas of the CNS. This critical anatomical position allows the thalamus to influence …

[HTML][HTML] Linking structure and function in macroscale brain networks

LE Suárez, RD Markello, RF Betzel, B Misic - Trends in cognitive sciences, 2020 - cell.com
Structure–function relationships are a fundamental principle of many naturally occurring
systems. However, network neuroscience research suggests that there is an imperfect link …

Human cognition involves the dynamic integration of neural activity and neuromodulatory systems

JM Shine, M Breakspear, PT Bell… - Nature …, 2019 - nature.com
The human brain integrates diverse cognitive processes into a coherent whole, shifting
fluidly as a function of changing environmental demands. Despite recent progress, the …

The cognitive thalamus as a gateway to mental representations

M Wolff, SD Vann - Journal of Neuroscience, 2019 - Soc Neuroscience
Historically, the thalamus has been viewed as little more than a relay, simply transferring
information to key players of the cast, the cortex and hippocampus, without providing any …

[HTML][HTML] Functional geometry of the cortex encodes dimensions of consciousness

Z Huang, GA Mashour, AG Hudetz - Nature communications, 2023 - nature.com
Consciousness is a multidimensional phenomenon, but key dimensions such as awareness
and wakefulness have been described conceptually rather than neurobiologically. We …

The thalamus integrates the macrosystems of the brain to facilitate complex, adaptive brain network dynamics

JM Shine - Progress in neurobiology, 2021 - Elsevier
The human brain is a complex, adaptive system comprised of billions of cells with trillions of
connections. The interactions between the elements of the system oppose this seemingly …

[HTML][HTML] The development of brain network hubs

S Oldham, A Fornito - Developmental cognitive neuroscience, 2019 - Elsevier
Some brain regions have a central role in supporting integrated brain function, marking them
as network hubs. Given the functional importance of hubs, it is natural to ask how they …

[HTML][HTML] Subcortical-cortical dynamical states of the human brain and their breakdown in stroke

C Favaretto, M Allegra, G Deco, NV Metcalf… - Nature …, 2022 - nature.com
The mechanisms controlling dynamical patterns in spontaneous brain activity are poorly
understood. Here, we provide evidence that cortical dynamics in the ultra-slow frequency …

[HTML][HTML] A set of functionally-defined brain regions with improved representation of the subcortex and cerebellum

BA Seitzman, C Gratton, S Marek, RV Raut… - Neuroimage, 2020 - Elsevier
An important aspect of network-based analysis is robust node definition. This issue is critical
for functional brain network analyses, as poor node choice can lead to spurious findings and …

The feasibility of artificial consciousness through the lens of neuroscience

J Aru, ME Larkum, JM Shine - Trends in Neurosciences, 2023 - cell.com
Interactions with large language models (LLMs) have led to the suggestion that these
models may soon be conscious. From the perspective of neuroscience, this position is …