[HTML][HTML] Kilohertz-frequency stimulation of the nervous system: A review of underlying mechanisms
Background Electrical stimulation in the kilohertz-frequency range has gained interest in the
field of neuroscience. The mechanisms underlying stimulation in this frequency range …
field of neuroscience. The mechanisms underlying stimulation in this frequency range …
Responses of model cortical neurons to temporal interference stimulation and related transcranial alternating current stimulation modalities
Objective. Temporal interference stimulation (TIS) was proposed as a non-invasive, focal,
and steerable deep brain stimulation method. However, the mechanisms underlying …
and steerable deep brain stimulation method. However, the mechanisms underlying …
High-frequency epidural electrical stimulation reduces spasticity and facilitates walking recovery in patients with spinal cord injury
Spinal cord injury (SCI) causes severe motor and sensory deficits, and there are currently no
approved treatments for recovery. Nearly 70% of patients with SCI experience pathological …
approved treatments for recovery. Nearly 70% of patients with SCI experience pathological …
Towards a more accurate quasi-static approximation of the electric potential for neurostimulation with kilohertz-frequency sources
Objective. Our goal was to determine the conditions for which a more precise calculation of
the electric potential than the quasi-static approximation may be needed in models of …
the electric potential than the quasi-static approximation may be needed in models of …
Spatiotemporal parameters for energy efficient kilohertz-frequency nerve block with low onset response
Background Electrical nerve conduction block has great potential for treatment of disease
through reversible and local inactivation of somatic and autonomic nerves. However, the …
through reversible and local inactivation of somatic and autonomic nerves. However, the …
Non-monotonic kilohertz frequency neural block thresholds arise from amplitude-and frequency-dependent charge imbalance
Reversible block of nerve conduction using kilohertz frequency electrical signals has
substantial potential for treatment of disease. However, the ability to block nerve fibers …
substantial potential for treatment of disease. However, the ability to block nerve fibers …
Membrane depolarization mediates both the inhibition of neural activity and cell-type-differences in response to high-frequency stimulation
Neuromodulation using high frequency (> 1 kHz) electric stimulation (HFS) enables
preferential activation or inhibition of individual neural types, offering the possibility of more …
preferential activation or inhibition of individual neural types, offering the possibility of more …
Computational models of compound nerve action potentials: Efficient filter-based methods to quantify effects of tissue conductivities, conduction distance, and nerve …
Background Peripheral nerve recordings can enhance the efficacy of neurostimulation
therapies by providing a feedback signal to adjust stimulation settings for greater efficacy or …
therapies by providing a feedback signal to adjust stimulation settings for greater efficacy or …
Effects of waveform shape and electrode material on KiloHertz frequency alternating current block of mammalian peripheral nerve
Objectives KiloHertz frequency alternating current waveforms produce conduction block in
peripheral nerves. It is not clearly known how the waveform shape affects block outcomes …
peripheral nerves. It is not clearly known how the waveform shape affects block outcomes …
IC-based neuro-stimulation environment for arbitrary waveform generation
Electrical stimulation of the nervous system is commonly based on biphasic stimulation
waveforms, which limits its relevance for some applications, such as selective stimulation …
waveforms, which limits its relevance for some applications, such as selective stimulation …