Local and long-range input balance: A framework for investigating frontal cognitive circuit maturation in health and disease
SJ Allen, H Morishita - Science Advances, 2024 - science.org
Frontal cortical circuits undergo prolonged maturation across childhood and adolescence;
however, it remains unknown what specific changes are occurring at the circuit level to …
however, it remains unknown what specific changes are occurring at the circuit level to …
Inhibition of noradrenergic signalling in rodent orbitofrontal cortex impairs the updating of goal-directed actions
In a constantly changing environment, organisms must track the current relationship
between actions and their specific consequences and use this information to guide decision …
between actions and their specific consequences and use this information to guide decision …
The rapid antidepressant effect of acupuncture on two animal models of depression by inhibiting M1-Ach receptors regulates synaptic plasticity in the prefrontal cortex
B Ning, Z Wang, J He, Q Wu, Q Deng, Q Yang, J Gao… - Brain Research, 2024 - Elsevier
Background It is unclear whether acupuncture has a rapid antidepressant effect and what is
the main mechanism. Methods In this study, forced swimming stress test (FST) in mice were …
the main mechanism. Methods In this study, forced swimming stress test (FST) in mice were …
Adaptive Responding to Stimulus–Outcome Associations Requires Noradrenergic Transmission in the Medial Prefrontal Cortex
A dynamic environment, such as the one we inhabit, requires organisms to continuously
update their knowledge of the setting. While the prefrontal cortex is recognized for its pivotal …
update their knowledge of the setting. While the prefrontal cortex is recognized for its pivotal …
Rhythmic oscillations in the midbrain dopaminergic nuclei in mice
VJ Oberto, J Matsumoto, MN Pompili… - Frontiers in Cellular …, 2023 - frontiersin.org
Introduction Dopamine release in the forebrain by midbrain ventral tegmental nucleus (VTA)
and substantia nigra pars compacta (SNc) neurons is implicated in reward processing, goal …
and substantia nigra pars compacta (SNc) neurons is implicated in reward processing, goal …
Physical exercise induces mental flow related to catecholamine levels in noncompetitive, but not competitive conditions in men
The study aimed to reveal physical exercise conditions and catecholamine response-
dependent differences while an individual experiences a flow state (FS) following …
dependent differences while an individual experiences a flow state (FS) following …
Behavioral Interventions Can Improve Brain Injury-Induced Deficits in Behavioral Flexibility and Impulsivity Linked to Impaired Reward-Feedback Beta Oscillations
MF Koloski, CM O'Hearn, M Frankot… - Journal of …, 2024 - liebertpub.com
Traumatic brain injury (TBI) affects a large population, resulting in severe cognitive
impairments. Although cognitive rehabilitation is an accepted treatment for some deficits …
impairments. Although cognitive rehabilitation is an accepted treatment for some deficits …
Locus coeruleus modulation of prefrontal dynamics and encoding of flexible rule switching
Behavioral flexibility, the ability to adjust behavioral strategies in response to changing
environmental contingencies and internal demands, is fundamental to cognitive functions …
environmental contingencies and internal demands, is fundamental to cognitive functions …
Noradrenergic signaling in the rodent orbitofrontal cortex is required to update goal-directed actions
In a constantly changing environment, organisms must track the current relationship
between actions and their specific consequences and use this information to guide decision …
between actions and their specific consequences and use this information to guide decision …
Alternative approaches to understanding habit learning in the dorsolateral striatum
Our daily lives are full of habits. Yet, even though we know them intimately, habits are
surprisingly hard to pin down in laboratory settings in order to study them and their basis in …
surprisingly hard to pin down in laboratory settings in order to study them and their basis in …