Peroxisome proliferator-activated receptor-targeted therapies: Challenges upon infectious diseases

IS Kim, P Silwal, EK Jo - Cells, 2023 - mdpi.com
Peroxisome proliferator-activated receptors (PPARs) α, β, and γ are nuclear receptors that
orchestrate the transcriptional regulation of genes involved in a variety of biological …

Promising role of peroxisome proliferator-activated receptors in respiratory disorders, a review

S Beigoli, S Kiani, F Asgharzadeh… - Drug Metabolism …, 2024 - Taylor & Francis
Several studies indicate various pharmacological and therapeutic effects of peroxisome
proliferator-activated receptors (PPARs) in different disorders. The current review describes …

Iso-seco-tanapartholide from Artemisia argyi inhibits the PFKFB3-mediated glycolytic pathway to attenuate airway inflammation in lipopolysaccharide-induced acute …

M Kong, D Zhu, J Dong, L Kong, J Luo - Journal of Ethnopharmacology, 2023 - Elsevier
Abstract Ethnopharmacological relevance In traditional Chinese folk medicine, Artemisia
argyi H. Lév. & Vaniot (A. argyi) has been used for thousands of years, and it is clinically …

[HTML][HTML] FOXK2 targeting by the SCF-E3 ligase subunit FBXO24 for ubiquitin mediated degradation modulates mitochondrial respiration

R El-Mergawy, L Chafin, JA Ovando-Ricardez… - Journal of Biological …, 2024 - Elsevier
FOXK2 is a crucial transcription factor implicated in a wide array of biological activities and
yet understanding of its molecular regulation at the level of protein turnover is limited. Here …

Topical adjunctive treatment with flagellin augments pulmonary neutrophil responses and reduces bacterial dissemination in multidrug-resistant K. pneumoniae …

CCA van Linge, RFJ Kullberg, O Chouchane… - Frontiers in …, 2024 - frontiersin.org
Objective Antimicrobial resistance is an emerging problem and multi-drug resistant (MDR)
Klebsiella pneumoniae (K. pneumoniae) represents an enormous risk of failing therapy in …

Pioglitazone and asthma: a review of current evidence

GI Barkas, ND Karakousis, KI Gourgoulianis… - Journal of …, 2024 - Taylor & Francis
Objective This review aims to present existing evidence on the impact of pioglitazone, a
thiazolidinedione class anti-diabetic drug, on asthma control and lung function, providing a …

Identification of Novel PPAR-β/δ Agonists from Kaempferol, Quercetin, and Resveratrol Derivatives by Targeting Cancer: An Integrative Molecular Docking and …

S Ballav, KB Lokhande, VK Sahu… - Letters in Drug …, 2024 - ingentaconnect.com
Background: Drug resistance in cancer is a serious threat to human well-being. There is a
dire need to develop novel and efficient lead molecules to treat the disease. In lieu of anti …

[PDF][PDF] SYSTEMIC EFFECT OF Tff3 PROTEIN DEFICIENCY IN LONG-TERM HIGH-FAT DIET MOUSE MODEL

I Bazina - mobi.unios.hr
SYSTEMIC EFFECT OF Tff3 PROTEIN DEFICIENCY IN LONG-TERM HIGH-FAT DIET
MOUSE MODEL Page 1 Josip Juraj Strossmayer University of Osijek University of Dubrovnik …