PIWI-interacting RNAs: small RNAs with big functions
In animals, PIWI-interacting RNAs (piRNAs) of 21–35 nucleotides in length silence
transposable elements, regulate gene expression and fight viral infection. piRNAs guide …
transposable elements, regulate gene expression and fight viral infection. piRNAs guide …
[HTML][HTML] Metazoan micrornas
DP Bartel - Cell, 2018 - cell.com
MicroRNAs (miRNAs) are∼ 22 nt RNAs that direct posttranscriptional repression of mRNA
targets in diverse eukaryotic lineages. In humans and other mammals, these small RNAs …
targets in diverse eukaryotic lineages. In humans and other mammals, these small RNAs …
MirGeneDB 2.1: toward a complete sampling of all major animal phyla
We describe an update of MirGeneDB, the manually curated microRNA gene database.
Adhering to uniform and consistent criteria for microRNA annotation and nomenclature, we …
Adhering to uniform and consistent criteria for microRNA annotation and nomenclature, we …
Nurse cell–derived small RNAs define paternal epigenetic inheritance in Arabidopsis
J Long, J Walker, W She, B Aldridge, H Gao, S Deans… - Science, 2021 - science.org
INTRODUCTION Epigenetic modifications to chromatin, such as the methylation of DNA
cytosines, carry regulatory information across the generations in plants and animals …
cytosines, carry regulatory information across the generations in plants and animals …
Pan-arthropod analysis reveals somatic piRNAs as an ancestral defence against transposable elements
In animals, small RNA molecules termed PIWI-interacting RNAs (piRNAs) silence
transposable elements (TEs), protecting the germline from genomic instability and mutation …
transposable elements (TEs), protecting the germline from genomic instability and mutation …
The Discovery, Distribution, and Evolution of Viruses Associated with Drosophila melanogaster
CL Webster, FM Waldron, S Robertson, D Crowson… - PLoS …, 2015 - journals.plos.org
Drosophila melanogaster is a valuable invertebrate model for viral infection and antiviral
immunity, and is a focus for studies of insect-virus coevolution. Here we use a metagenomic …
immunity, and is a focus for studies of insect-virus coevolution. Here we use a metagenomic …
No evidence for extensive horizontal gene transfer in the genome of the tardigrade Hypsibius dujardini
G Koutsovoulos, S Kumar… - Proceedings of the …, 2016 - National Acad Sciences
Tardigrades are meiofaunal ecdysozoans that are key to understanding the origins of
Arthropoda. Many species of Tardigrada can survive extreme conditions through …
Arthropoda. Many species of Tardigrada can survive extreme conditions through …
Diverse RNA viruses of parasitic nematodes can elicit antibody responses in vertebrate hosts
S Quek, A Hadermann, Y Wu, L De Coninck… - Nature …, 2024 - nature.com
Parasitic nematodes have an intimate, chronic and lifelong exposure to vertebrate tissues.
Here we mined 41 published parasitic nematode transcriptomes from vertebrate hosts and …
Here we mined 41 published parasitic nematode transcriptomes from vertebrate hosts and …
A single mechanism of biogenesis, initiated and directed by PIWI proteins, explains piRNA production in most animals
In animals, PIWI-interacting RNAs (piRNAs) guide PIWI proteins to silence transposons and
regulate gene expression. The mechanisms for making piRNAs have been proposed to …
regulate gene expression. The mechanisms for making piRNAs have been proposed to …
Silencing in sperm cells is directed by RNA movement from the surrounding nurse cell
Plant small interfering RNAs (siRNAs) communicate from cell to cell and travel long
distances through the vasculature. However, siRNA movement into germ cells has remained …
distances through the vasculature. However, siRNA movement into germ cells has remained …