From nano to micro to macro: Electrospun hierarchically structured polymeric fibers for biomedical applications

G Yang, X Li, Y He, J Ma, G Ni, S Zhou - Progress in Polymer Science, 2018 - Elsevier
Hierarchically structured polymer fibers encompassing 1-D, 2-D, and 3-D structures with at
least one dimension nano-to micro-meters in size have recently received an increasing …

Current advances in electrospun gelatin-based scaffolds for tissue engineering applications

AA Aldana, GA Abraham - International journal of pharmaceutics, 2017 - Elsevier
The development of biomimetic highly-porous scaffolds is essential for successful tissue
engineering. Electrospun nanofibers are highly versatile platforms for a broad range of …

Clinical-grade stem cell–derived retinal pigment epithelium patch rescues retinal degeneration in rodents and pigs

R Sharma, V Khristov, A Rising, BS Jha… - Science translational …, 2019 - science.org
Considerable progress has been made in testing stem cell–derived retinal pigment
epithelium (RPE) as a potential therapy for age-related macular degeneration (AMD) …

Biomimetic PCL-gelatin based nanofibers loaded with ciprofloxacin hydrochloride and quercetin: A potential antibacterial and anti-oxidant dressing material for …

G Ajmal, GV Bonde, P Mittal, G Khan… - International Journal of …, 2019 - Elsevier
An open wound is highly susceptible to microbial infection leading to elevated level of
inflammatory response. For prompt healing, a wound requires a biomimetic dressing …

[HTML][HTML] Stemming retinal regeneration with pluripotent stem cells

ZB Jin, ML Gao, WL Deng, KC Wu, S Sugita… - Progress in retinal and …, 2019 - Elsevier
Cell replacement therapy is a promising treatment for irreversible retinal cell death in diverse
diseases, such as age-related macular degeneration (AMD), Stargardt's disease, retinitis …

Interactions of the choroid, Bruch's membrane, retinal pigment epithelium, and neurosensory retina collaborate to form the outer blood-retinal-barrier

MA Fields, LV Del Priore, RA Adelman… - Progress in retinal and …, 2020 - Elsevier
The three interacting components of the outer blood-retinal barrier are the retinal pigment
epithelium (RPE), choriocapillaris, and Bruch's membrane, the extracellular matrix that lies …

Stem cell based therapies for age-related macular degeneration: the promises and the challenges

H Nazari, L Zhang, D Zhu, GJ Chader… - Progress in retinal and …, 2015 - Elsevier
Age-related macular degeneration (AMD) is the leading cause of blindness among the
elderly in developed countries. AMD is classified as either neovascular (NV-AMD) or non …

Gelatin nanofibers: Recent insights in synthesis, bio-medical applications and limitations

HR El-Seedi, NS Said, N Yosri, HB Hawash… - Heliyon, 2023 - cell.com
The use of gelatin and gelatin-blend polymers as environmentally safe polymers to
synthesis electrospun nanofibers, has caused a revolution in the biomedical field. The …

Progress of nanotechnology in diabetic retinopathy treatment

Y Liu, N Wu - International journal of nanomedicine, 2021 - Taylor & Francis
Diabetic retinopathy (DR) is a chronic diabetes complication that progressively manifests
itself as blurred vision, eye floaters, distorted vision, and even partial or total loss of vision as …

PLGA/Gelatin-based electrospun nanofiber scaffold encapsulating antibacterial and antioxidant molecules for accelerated tissue regeneration

G Ajmal, GV Bonde, P Mittal, VK Pandey… - Materials Today …, 2023 - Elsevier
A full-thickness or hard-to-heal wound pose a significant challenge in clinical feilds. These
wounds are very prone to microbial infection, lead to an elevated level of reactive oxygen …