Opioid-related mortality is a growing problem in the United States, and in 2015 there were
over 33,000 opioid-related deaths. To combat this mortality trend, naloxone is increasingly …

Naloxone is a well-established essential medicine for the treatment of life-threatening
heroin/opioid overdose in emergency medicine. Over two decades, the concept of 'take …

Background Opioid overdose is a major cause of mortality, but injury and fatal outcomes can
be prevented by timely administration of the opioid antagonist naloxone. Pre-provision of …

Background Opioid related overdoses and overdose deaths continue to constitute an urgent
public health crisis. The implementation of naloxone programs, such as 'take-home …

Fentanyl rose to prominence as an alternative analgesic to morphine nearly 50 years ago;
today, fentanyl has re-emerged as a dangerous recreational substance. The increased …

Aim: To assess the pharmacokinetic properties of community-use formulations of naloxone
for emergency treatment of opioid overdose. Methods: Systematic literature review based on …

Background: Heroin overdose is a major cause of premature death. Naloxone is an opioid
antagonist that is effective for the reversal of heroin overdose in emergency situations and …

Concomitant use of tobacco and opioids represents a growing public health concern. In fact,
the mortality rate due to smoking-related illness approaches 50% among SUD patients …

Naloxone (NAL) is administered parenterally or intranasally for treating opioid overdose.
The short duration of action of NAL calls for frequent re-dosing which may be eliminated by …

To provide an update on prescription of naloxone as a harm-reduction strategy, PubMed
was searched to identify publications relevant to naloxone prescribing for reversal of opioid …